LEADER 04639nam 2200637Ia 450 001 9910455941103321 005 20200520144314.0 010 $a1-280-21480-5 010 $a9786610214808 010 $a0-309-55775-5 010 $a0-585-14439-7 035 $a(CKB)110986584750836 035 $a(EBL)3377195 035 $a(SSID)ssj0000215468 035 $a(PQKBManifestationID)11202596 035 $a(PQKBTitleCode)TC0000215468 035 $a(PQKBWorkID)10194336 035 $a(PQKB)10198298 035 $a(MiAaPQ)EBC3377195 035 $a(Au-PeEL)EBL3377195 035 $a(CaPaEBR)ebr10068430 035 $a(CaONFJC)MIL21480 035 $a(OCoLC)940510378 035 $a(EXLCZ)99110986584750836 100 $a19890811d1989 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aOpportunities in biology$b[electronic resource] /$fCommittee on Research Opportunities in Biology, Board in Biology, Commission on Life Sciences, National Research Council 210 $aWashington $cNational Academy Press$d1989 215 $a1 online resource (470 p.) 300 $aIncludes index. 311 $a0-309-07881-4 311 $a0-309-03927-4 320 $aIncludes bibliographical references (p. 422-423). 327 $aOpportunities in Biology; Copyright; Acknowledgments; Preface; Contents; Executive Summary; THE NEW BIOLOGY; STRUCTURAL BIOLOGY; GENES AND CELLS; DEVELOPMENT; THE NERVOUS SYSTEM AND BEHAVIOR; THE IMMUNE SYSTEM AND INFECTIOUS DISEASES; EVOLUTION, SYSTEMATICS, AND ECOLOGY; PLANT BIOLOGY AND AGRICULTURE; INFRASTRUCTURE OF BIOLOGY RESEARCH AND RECOMMENDATIONS; Training; Equipment and Facilities; Funding; Information Science and Collections; International Cooperation; 1 The New Biology; DIVISIONS BETWEEN TRADITIONAL DISCIPLINES ARE BEING REMOVED; 2 New Technologies and Instrumentation 327 $aRECOMBINANT DNA TECHNIQUESRecombinant DNA Techniques Permit us to Isolate a Single Gene From the Tens of Thousands Encoded in a Complex Genome; Transformation of Higher Organisms; Biologists Can Specifically Insert a Functioning Gene Into the Genome of Complex Organisms; Making a Transgenic Animal; A Transgenic Animal is Produced Initially by a Combination of Microsurgery And Embryological Techniques; Transgenic Mice Have Been Used For a Variety of Experiments; Creating Transgenic Plants; The Creation of Transformed Plants Has Been one of The Most Exciting Developments in Modern Biology 327 $aFuture ProspectsThe Potential for Using Transgenic Organisms to Make Discoveries Over the Next 5 or 10 Years Is Vast; MONOCLONAL ANTIBODIES; Monoclonal Antibodies Can be Used as Biological Probes For Specific Molecules; MICROCHEMICAL TECHNIQUES; Microchemical Instrumentation Has Had a Powerful Impact on Modern Biology That is Just Beginning to be Felt; FLOW CYTOMETRY; Flow Cytometry is Used to Sort Cells; MICROSCOPY; A Revolution in the Application of Light Microscopy Has Occurred; Video-Enhanced Contrast Microscopy 327 $aVideo-Enhanced Contrast Microscopy Combines the Technologies of Modern Light Microscopy, Video Imaging, and Digital Image...Low-Light-Dose Microscopy; Coupling Biological Chemistry with Advanced Image Processing Has Permitted Low-Light-Dose Microscopy to Evolve as an...; Scanning Acoustic Microscope; The Scanning Acoustic Microscope Measures the Elastic Properties of the Cell; Scanning Tunneling and Atomic Force Microscope; The Scanning Tunneling Microscope Allows One to Image Surfaces with the Resolution of an Few Angstroms 327 $aThe Atomic Force Microscope Holds Great Promise for Analyzing Biological SpecimensMAGNETIC RESONANCE; Magnetic Resonance Spectroscopy is Becoming an Invaluable Tool for Determining the Structures of Complex Molecules; COMPUTERS AND DATA ANALYSIS; Computers are Coming to Play an Central Role in Modern Biology; BIOLOGY AND THE FUTURE; Synergistic Interactions of the New Biology Have Shortened the Time Between Fundamental Observations and Applications; 3 Molecular Structure and Function; Biological Macromolecules are Machines 327 $aThe Main Theme of Structural Biology Is the Relation of Molecular Structure to Function 606 $aBiology$xResearch 606 $aLife sciences$xResearch 608 $aElectronic books. 615 0$aBiology$xResearch. 615 0$aLife sciences$xResearch. 676 $a574/.072 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910455941103321 996 $aOpportunities in biology$92092916 997 $aUNINA