LEADER 02558nam 2200613Ia 450 001 9910455259903321 005 20200520144314.0 010 $a1-84755-833-X 035 $a(CKB)1000000000791426 035 $a(EBL)1185200 035 $a(OCoLC)319518576 035 $a(SSID)ssj0000352701 035 $a(PQKBManifestationID)12125599 035 $a(PQKBTitleCode)TC0000352701 035 $a(PQKBWorkID)10303239 035 $a(PQKB)10500357 035 $a(MiAaPQ)EBC1185200 035 $a(PPN)198478984 035 $a(Au-PeEL)EBL1185200 035 $a(CaPaEBR)ebr10618684 035 $a(CaONFJC)MIL872359 035 $a(EXLCZ)991000000000791426 100 $a20080923d2008 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aBile acids$b[electronic resource] $etoxicology and bioactivity /$fedited by Gareth Jenkins, Laura J. Hardie 210 $aCambridge $cSC Pub.$dc2008 215 $a1 online resource (176 p.) 225 0$aIssues in toxicology 300 $aDescription based upon print version of record. 311 $a0-85404-846-4 320 $aIncludes bibliographical references and index. 327 $aPublicity_9780854048465; i_iv; v_vi; vii_xii; 001_013; 014_047; 048_071; 072_083; 084_099; 100_121; 122_140; 141_158; 159_163 330 $aBile acids are increasingly being seen as extremely important carcinogenic agents in cancers of the bile duct, liver, colon, rectum, and oesophagus. They are essential agents involved in lipid digestion and absorption in mammals, however, they also play wide-ranging roles in a variety of disease states ranging from diabetes to cancer. They have evolved exquisite mechanisms for controlling their own synthesis and to ensure that they are produced at correct concentrations and also kept in the correct anatomical environment. It is only when these fine levels of controls are breached that Bile aci 410 0$aIssues in Toxicology 606 $aBile acids$xPhysiological effect 606 $aBile acids$xToxicology 608 $aElectronic books. 615 0$aBile acids$xPhysiological effect. 615 0$aBile acids$xToxicology. 676 $a612/.01577 700 $aJenkins$b Gareth$g(Gareth J.)$0870470 701 $aHardie$b Laura J$0870471 712 02$aRoyal Society of Chemistry (Great Britain) 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910455259903321 996 $aBile acids$91943152 997 $aUNINA