LEADER 03884nam 2200757 a 450 001 9910454420903321 005 20200520144314.0 010 $a1-281-30751-3 010 $a9786611307516 010 $a92-4-068249-X 035 $a(CKB)1000000000689235 035 $a(EBL)329002 035 $a(OCoLC)213772601 035 $a(SSID)ssj0000294931 035 $a(PQKBManifestationID)12071167 035 $a(PQKBTitleCode)TC0000294931 035 $a(PQKBWorkID)10315392 035 $a(PQKB)10095882 035 $a(MiAaPQ)EBC329002 035 $a(Au-PeEL)EBL329002 035 $a(CaPaEBR)ebr10214528 035 $a(CaONFJC)MIL130751 035 $a(EXLCZ)991000000000689235 100 $a20081023d2006 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aElemental speciation in human health risk assessment$b[electronic resource] /$ffirst draft prepared by P. Apostoli ... [et al.] 210 $aGeneva $cWorld Health Organization$d2006 215 $a1 online resource (256 p.) 225 1 $aEnvironmental health criteria,$x0250-863X ;$v234 300 $a"Published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organization and the World Health Organization, and produced within the framework of the Inter-Organization Programme for the Sound Management of Chemicals." 311 $a92-4-157234-5 320 $aIncludes bibliographical references and index. 327 $aTITLE; COPYRIGHT; CONTENTS; NOTE TO READERS OF THE CRITERIA MONOGRAPHS; PREAMBLE; WHO TASK GROUP ON ENVIRONMENTAL HEALTH CRITERIA FOR ELEMENTAL SPECIATION IN HUMAN HEALTH RISK ASSESSMENT; ACRONYMS AND ABBREVIATIONS; 1. SUMMARY; 2. DEFINITIONS OF SPECIES AND SPECIATION; 3. STRUCTURAL ASPECTS OF SPECIATION; 4. ANALYTICAL TECHNIQUES AND METHODOLOGY; 5. BIOACCESSIBILITY AND BIOAVAILABILITY; 6. TOXICOKINETICS AND BIOLOGICAL MONITORING; 7. MOLECULAR AND CELLULAR MECHANISMS OF METAL TOXICITY; 8. HEALTH EFFECTS; 9. CONCLUSIONS AND RECOMMENDATIONS; REFERENCES; RESUME; RESUMEN; INDEX OF ELEMENTS; 330 $aThe purpose of this book is to assess, evaluate, and give guidance on the role of elemental speciation and speciation analysis in human health hazard and risk assessment. The book is directed at risk assessors and regulators, to emphasize the importance of consideration of speciation in their deliberations. To date, this issue has not been a part of most hazard and risk assessments. Further aims of the publication are to encourage the analysis of speciation of elements to increase knowledge on the effect of speciation on mode of action and to increase understanding of health effects. 410 0$aEnvironmental health criteria ;$v234. 606 $aTrace elements$xSpeciation 606 $aHealth risk assessment 606 $aBiological monitoring 606 $aBioavailability 606 $aAnalytical toxicology 606 $aChemical elements$xPhysiological effect 608 $aElectronic books. 615 0$aTrace elements$xSpeciation. 615 0$aHealth risk assessment. 615 0$aBiological monitoring. 615 0$aBioavailability. 615 0$aAnalytical toxicology. 615 0$aChemical elements$xPhysiological effect. 676 $a615.9515 701 $aApostoli$b P$g(Pietro)$0915216 712 02$aInternational Program on Chemical Safety. 712 02$aWorld Health Organization. 712 02$aUnited Nations Environment Programme. 712 02$aInternational Labour Organisation. 712 02$aInter-Organization Programme for the Sound Management of Chemicals. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910454420903321 996 $aElemental speciation in human health risk assessment$92051119 997 $aUNINA LEADER 01139nas 2200433 c 450 001 9910146891803321 005 20240131152826.0 011 $a2146-0108 035 $a(CKB)1000000000293359 035 $a(OCoLC)213487721 035 $a(OCoLC)434810448 035 $a(OCoLC)712564843 035 $a(OCoLC)711865741 035 $a(DE-101)987472291 035 $a(DE-599)ZDB2409040-2 035 $a(EXLCZ)991000000000293359 100 $a20080208a20079999 |y | 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aJournal of applied biological sciences$eJABS 210 31$aAnkara$cNobel Publ.$d2007- 215 $aOnline-Ressource 300 $aGesehen am 18.09.20 311 08$a1307-1130 517 3 $aJABS 531 $aJ APPL BIOL SCI 608 $aZeitschrift$2gnd-content 676 $a570 686 $aBIODIV$qDE-30$2fid 801 0$b8999 801 1$bDE-101 801 2$b9001 906 $aJOURNAL 912 $a9910146891803321 996 $aJournal of applied biological sciences$92203078 997 $aUNINA