LEADER 00715oam 2200193z- 450 001 996396996603316 005 20200818211258.0 035 $a(CKB)4940000000056169 035 $a(EEBO)2240956363 035 $a(EXLCZ)994940000000056169 100 $a20191209c1675uuuu -u- - 101 0 $aeng 200 14$aThe mulberry-garden, a comedy as it is acted by His Majestie's servants at the Theatre-Royal / written by the Honourable Sir Charles Sidley 210 $aEngland$cPrinted for H. Herringman 700 $aSedley$b Charles, Sir$01004101 906 $aBOOK 912 $a996396996603316 996 $aThe mulberry-garden, a comedy as it is acted by His Majestie's servants at the Theatre-Royal$92306169 997 $aUNISA LEADER 03458nam 2200685 a 450 001 9910454294603321 005 20200520144314.0 010 $a0-7619-6620-X 010 $a1-282-02056-0 010 $a9786612020568 010 $a1-84920-218-4 035 $a(CKB)1000000000716273 035 $a(EBL)420899 035 $a(OCoLC)476254368 035 $a(SSID)ssj0000253178 035 $a(PQKBManifestationID)11239868 035 $a(PQKBTitleCode)TC0000253178 035 $a(PQKBWorkID)10187050 035 $a(PQKB)10167579 035 $a(MiAaPQ)EBC420899 035 $a(OCoLC)320930719 035 $a(StDuBDS)EDZ0000064081 035 $a(Au-PeEL)EBL420899 035 $a(CaPaEBR)ebr10285259 035 $a(CaONFJC)MIL202056 035 $a(EXLCZ)991000000000716273 100 $a20120327d2000 fy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aSubject leadership and school improvement$b[electronic resource] /$fHugh Busher and Alma Harris with Christine Wise 210 $aLondon $cPaul Chapman$d2000 215 $a1 online resource (225 p.) 225 1 $aPublished in association with the British Educational Leadership and Management Society 300 $aDescription based upon print version of record. 311 $a1-4462-1983-6 311 $a0-7619-6621-8 320 $aIncludes bibliographical references (p. 197-210) and index. 327 $aCover; Copyright; Contents; Series Editor's Preface; Preface; Acknowledgements; 1 Introduction; Part I Strategic Direction and Development of the Subject Area; 2 Managing Change within the Subject Area; 3 Managing Federal and Confederate Departments; 4 Leading and Co-ordinating Diffuse Subject Areas; Part II Teaching and Learning; 5 Being a Curriculum Leader: Helping Colleagues to Improve Learning; 6 Improving Teaching and Learning within the Subject Area; 7 Developing Professional Networks:Working with Parents and Communities to Enhance Students' Learning; Part III Leading and Managing Staff 327 $a8 The Subject Leader as a Middle Manager9 Cultures of Leadership and ProfessionalAutonomy: Managing Self, Developing Others; 10 Professional Development and Action Research; Part IV Efficient and Effective Deployment of Staff and Resources; 11 Planning Development and ResourceUtilisation to Improve Students'Learning; 12 Working with Support and Supply Staff to Improve School Performance; 13 Subject Leadership and School Improvement; References; Index 330 8 $aThis volume debates the functions of subject leaders using current research-based conceptual frameworks. It considers how subject leaders can bring about improvement and change in schools and looks at the management processes. 410 0$aPublished in association with the British Educational Leadership and Management Society 606 $aCurriculum planning$zGreat Britain 606 $aSchool improvement programs$zGreat Britain 608 $aElectronic books. 615 0$aCurriculum planning 615 0$aSchool improvement programs 676 $a375 676 $a375.0010941 700 $aBusher$b Hugh$0924582 701 $aHarris$b Alma$f1958-$0857636 701 $aWise$b Christine$01055765 801 0$bStDuBDS 801 1$bStDuBDS 906 $aBOOK 912 $a9910454294603321 996 $aSubject leadership and school improvement$92489417 997 $aUNINA LEADER 05238nam 2200673Ia 450 001 9910144008303321 005 20170810192822.0 010 $a1-282-37220-3 010 $a9786612372209 010 $a3-527-62021-4 010 $a3-527-62036-2 035 $a(CKB)1000000000376040 035 $a(EBL)481470 035 $a(OCoLC)741346724 035 $a(SSID)ssj0000307206 035 $a(PQKBManifestationID)11238766 035 $a(PQKBTitleCode)TC0000307206 035 $a(PQKBWorkID)10244368 035 $a(PQKB)10148525 035 $a(MiAaPQ)EBC481470 035 $a(EXLCZ)991000000000376040 100 $a20060807d2006 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aProtein degradation$hVolume 2$iThe Ubiquitin-proteasome system$b[electronic resource] /$fR. John Mayer, Aaron Ciechanover, Martin Rechsteiner, eds 210 $aWeinheim $cWiley-VCH$dc2006 215 $a1 online resource (302 p.) 225 1 $aProtein Degradation ;$vv.9 300 $aDescription based upon print version of record. 311 $a3-527-31130-0 320 $aIncludes bibliographical references and index. 327 $aProtein Degradation; Contents; Preface; List of Contributors; 1 Molecular Chaperones and the Ubiquitin-Proteasome System; 1.1 Introduction; 1.2 A Biomedical Perspective; 1.3 Molecular Chaperones: Mode of Action and Cellular Functions; 1.3.1 The Hsp70 Family; 1.3.2 The Hsp90 Family; 1.3.3 The Small Heat Shock Proteins; 1.3.4 Chaperonins; 1.4 Chaperones: Central Players During Protein Quality Control; 1.5 Chaperones and Protein Degradation; 1.6 The CHIP Ubiquitin Ligase: A Link Between Folding and Degradation Systems 327 $a1.7 Other Proteins That May Influence the Balance Between Chaperone-assisted Folding and Degradation1.8 Further Considerations; 1.9 Conclusions; References; 2 Molecular Dissection of Autophagy in the Yeast Saccharomyces cerevisiae; 2.1 Introduction; 2.2 Vacuoles as a Lytic Compartment in Yeast; 2.3 Discovery of Autophagy in Yeast; 2.4 Genetic Dissection of Autophagy; 2.5 Characterization of Autophagy-defective Mutants; 2.6 Cloning of ATG Genes; 2.7 Further Genes Required for Autophagy; 2.8 Selectivity of Proteins Degraded; 2.9 Induction of Autophagy; 2.10 Membrane Dynamics During Autophagy 327 $a2.11 Monitoring Methods of Autophagy in the Yeast S. cerevisiae2.12 Function of Atg Proteins; 2.12.1 The Atg12 Protein Conjugation System; 2.12.2 The Atg8 System; 2.12.3 The Atg1 Kinase Complex; 2.12.4 Autophagy-specific PI3 Kinase Complex; 2.12.5 Other Atg Proteins; 2.13 Site of Atg Protein Functioning: The Pre-autophagosomal Structure; 2.14 Atg Proteins in Higher Eukaryotes; 2.15 Atg Proteins as Markers for Autophagy in Mammalian Cells; 2.16 Physiological Role of Autophagy in Multicellular Organisms; 2.17 Perspectives; References 327 $a3 Dissecting Intracellular Proteolysis Using Small Molecule Inhibitors and Molecular Probes3.1 Introduction; 3.2 The Proteasome as an Essential Component of Intracellular Proteolysis; 3.3 Proteasome Structure, Function, and Localization; 3.4 Proteasome Inhibitors as Tools to Study Proteasome Function; 3.4.1 Peptide Aldehydes; 3.4.2 Lactacystin; 3.4.3 Peptide Epoxyketones; 3.4.4 Cyclic Peptides; 3.4.5 Peptide Boronates; 3.4.6 Peptide Vinyl Sulfones; 3.4.7 Peptide Vinyl Sulfones as Proteasomal Activity Probes 327 $a3.4.8 Future Directions in the Development of Inhibitors of the Proteasome's Proteolytic Activities3.5 Assessing the Biological Role of the Proteasome With Inhibitors and Probes; 3.6 Proteasome-associated Components: The Role of N-glycanase; 3.7 A Link Between Proteasomal Proteolysis and Deubiquitination; 3.7.1 Reversal of Ub Modification; 3.7.2 Ubiquitin-specific Proteases; 3.7.3 USP Reactive Probes Correlate USP Activity With Proteasomal Proteolysis; 3.8 Future Developments and Final Remarks; Acknowledgments; Abbreviations; References 327 $a4 MEKK1: Dual Function as a Protein Kinase and a Ubiquitin Protein Ligase 330 $aThe second volume in a new series dedicated to protein degradation, this book discusses the mechanism and cellular functions of targeted protein breakdown via the ubiquitin pathway.Drawing on the combined knowledge of the world's leading protein degradation experts, this handy reference compiles information on the proteasome-mediated degradation steps of the ubiquitin pathway. In addition to proteasomal function and regulation, it also presents the latest results on novel members of the ubiquitin superfamily and their role in cellular regulation.Further volumes in the series cover the 410 0$aProtein Degradation 606 $aProteins$xMetabolism 606 $aUbiquitin 608 $aElectronic books. 615 0$aProteins$xMetabolism. 615 0$aUbiquitin. 676 $a572.76 676 $a612.3/98 701 $aMayer$b R. J$0867090 701 $aCiechanover$b Aaron J$0867091 701 $aRechsteiner$b Martin$0867092 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910144008303321 996 $aProtein degradation$91935375 997 $aUNINA