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100   $a20090514d2008      uy             0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aTowards drugs of the future$b[electronic resource] $ekey issues in lead finding and lead optimization /$fedited by C.G. Kruse and H. Timmerman
210   $aAmsterdam $cIOS Press$d2008
215   $a1 online resource (140 p.)
225 1 $aSolvay Pharmaceuticals Conferences,$x1566-7685 ;$vv. 9
300   $aDescription based upon print version of record.
311   $a1-58603-949-0 
320   $aIncludes bibliographical references and index.
327   $aTitle page; Preface; List of Contributors; Contents; Conference Preface and Keynote Lecture; A Thermodynamic Platform for Drug Discovery and Optimization; Structure-Based Design: Past, Present, and Future; Sense and Nonsense in Drug Discovery: A Chemical Perspective; Synthesis at the Interface of Chemistry and Biology: How and Why?; Drug Design with ADME in Mind: Recent Paradigm Shifts in Drug Discovery; Hypothesis Generation for Scientific Discovery. Examples from the Use of KEMŽ, a Rule-Based Method for Multi-Objective Analysis and Optimization
327   $aDoes Size Matter? Facts and Thoughts on Recombinant DrugsCan Nanotechnology Improve the Oral Delivery of Therapeutic Proteins?; The Omeprazole Story: How Endurance in Research May Pay Off; Conceptual Design of Cannabinoid CB1 Receptor Antagonists; Author Index
330   $aThe number of novel medications in the global industry pipeline is insufficient to suffice demand of the markets, the financial performance of several companies is declining, and sales and marketing costs are rising. This title addresses the development in synthetic and medicinal chemistry with the emphasis on global challenges.
410  0$aSolvay Pharmaceuticals Conferences ;$vv. 9.
606   $aPharmaceutical chemistry$vCongresses
606   $aDrug development$vCongresses
606   $aPharmaceutical industry$vCongresses
608   $aElectronic books.
615  0$aPharmaceutical chemistry
615  0$aDrug development
615  0$aPharmaceutical industry
676   $a615.1072
701   $aKruse$b C. G$g(Chris G.),$f1952-$0927044
701   $aTimmerman$b H$g(Hendrick)$091935
712 02$aSolvay Pharmaceuticals.
712 12$aSolvay Pharmaceutical Conference on Medicinal Chemistry
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910454034503321
996   $aTowards drugs of the future$92082696
997   $aUNINA