LEADER 03437nam 2200613Ia 450 001 9910453878303321 005 20200520144314.0 010 $a1-281-81831-3 010 $a9786611818319 010 $a0-8261-6488-9 035 $a(CKB)1000000000705082 035 $a(EBL)423514 035 $a(OCoLC)437109844 035 $a(SSID)ssj0000356642 035 $a(PQKBManifestationID)11256514 035 $a(PQKBTitleCode)TC0000356642 035 $a(PQKBWorkID)10349931 035 $a(PQKB)11250538 035 $a(MiAaPQ)EBC423514 035 $a(Au-PeEL)EBL423514 035 $a(CaPaEBR)ebr10265346 035 $a(EXLCZ)991000000000705082 100 $a19901210d1990 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aAnnual review of gerontology and geriatrics$hVolume 10$iSpecial focus on the biology of aging$b[electronic resource] /$fVincent J. Cristofalo, special volume editor 210 $aNew York $cSpringer$dc1990 215 $a1 online resource (240 p.) 225 1 $aAnnual review of gerontology and geriatrics,$x0198-8794 ;$vv. 10, 1990 300 $aDescription based upon print version of record. 311 $a0-8261-6492-7 320 $aIncludes bibliographical references and index. 327 $aContents; Foreword; Preface; Contributors; Forthcoming Contents, Volume 11; Chapter 1 Overview of Biological Mechanism of Aging; Chapter 2 Genetic Diseases of Premature Aging as Models of Senescence; Chapter 3 Growth Factors and Cell Aging; Chapter 4 Role of Endogenous Proteins as Negative Growth Modulators During In Vitro Cellular Aging of Human Diploid Fibroblasts; Chapter 5 T-Cell Function in Aging: Mechanisms of Decline; Chapter 6 Molecular Genetic Approaches to Mechanisms of Senescence; Chapter 7 Altered Protein Metabolism in Aging 327 $aChapter 8 Mechanisms of Altered Hormone-Neurotransmitter Action During Aging: From Receptors to Calcium MobilizationChapter 9 Skeletal Muscle Weakness and Fatigue in Old Age: Underlying Mechanisms; Chapter 10 Vulnerability of Neuronal Cytoskeleton in Aging and Alzheimer Disease: Widespread Involvement of All Three Major Filament Systems; Chapter 11 Dietary Restriction as a Probe of Mechanisms of Senescence; Chapter 12 Role of Free Radicals in Senescence; Index 330 $aThis volume presents a clear, concise overview of the current state of knowledge about the biology of aging - serving as both an invaluable graduate-level text and a key reference for practicing professionals. Over a dozen distinguished contributors probe the latest developments in our knowledge of why people age and how the process works. These authoritative chapters are not just written for biologists - but for gerontologists in general. Marks the tenth anniversary of the Annual Review of Gerontology and Geriatrics. 410 0$aAnnual review of gerontology and geriatrics ;$vv. 10, 1990. 606 $aAging$xPhysiological aspects 606 $aGeriatrics 608 $aElectronic books. 615 0$aAging$xPhysiological aspects. 615 0$aGeriatrics. 676 $a362.5 676 $a362.5/05 701 $aCristofalo$b Vincent J.$f1933-$092071 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910453878303321 996 $aAnnual review of gerontology and geriatrics$92273318 997 $aUNINA