LEADER 04446nam 2200745 450 001 9910453543703321 005 20200520144314.0 010 $a0-691-11534-6 010 $a1-4008-5073-8 024 7 $a10.1515/9781400850730 035 $a(CKB)2550000001192462 035 $a(EBL)1538264 035 $a(SSID)ssj0001156537 035 $a(PQKBManifestationID)11663786 035 $a(PQKBTitleCode)TC0001156537 035 $a(PQKBWorkID)11200328 035 $a(PQKB)10095502 035 $a(MiAaPQ)EBC1538264 035 $a(OCoLC)874157957 035 $a(MdBmJHUP)muse37229 035 $a(DE-B1597)447459 035 $a(OCoLC)979911000 035 $a(DE-B1597)9781400850730 035 $a(Au-PeEL)EBL1538264 035 $a(CaPaEBR)ebr10833847 035 $a(CaONFJC)MIL571930 035 $a(OCoLC)869520049 035 $a(EXLCZ)992550000001192462 100 $a20140212h20032003 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aDismantling democratic states /$fEzra Suleiman 205 $aCourse Book 210 1$aPrinceton, New Jersey :$cPrinceton University Press,$d2003. 210 4$dİ2003 215 $a1 online resource (342 p.) 300 $aIncludes index. 311 $a1-306-40679-X 311 $a0-691-12251-2 320 $aIncludes bibliographical references and index. 327 $t Frontmatter -- $tContents -- $tAcknowledgments -- $tIntroduction -- $tChapter 1. The End of Bureaucracy? -- $tChapter 2. Beyond Weber? -- $tChapter 3. New Conceptions of Bureaucracy, Democracy, and Citizenship -- $tChapter 4. Popular Dissatisfaction and Administrative Reform -- $tChapter 5. Universalistic Reforms -- $tChapter 6. Emulating the Private Sector -- $tChapter 7. The Reluctant Reformers: Japan and France -- $tChapter 8. Deprofessionalization: The Decline of the Civil Service Career -- $tChapter 9. Deprofessionalization: The Process of Politicization -- $tChapter 10. The End of the Nonpolitical Bureaucracy -- $tChapter 11. Constructing a Bureaucratic Apparatus in East-Central Europe -- $tChapter 12. The Politics of Bureaucratic Reform -- $tIndex 330 $aBureaucracy is a much-maligned feature of contemporary government. And yet the aftermath of September 11 has opened the door to a reassessment of the role of a skilled civil service in the survival and viability of democratic society. Here, Ezra Suleiman offers a timely and powerful corrective to the widespread view that bureaucracy is the source of democracy's ills. This is a book as much about good governance as it is about bureaucratic organizations. Suleiman asks: Is democratic governance hindered without an effective instrument in the hands of the legitimately elected political leadership? Is a professional bureaucracy required for developing but not for maintaining a democratic state? Why has a reform movement arisen in recent years championing the gradual dismantling of bureaucracy, and what are the consequences? Suleiman undertakes a comparative analysis of the drive toward a civil service grounded in the New Public Management. He argues that "government reinvention" has limited bureaucracy's capacity to adequately serve the public good. All bureaucracies have been under political pressure in recent years to reduce not only their size but also their effectiveness, and all have experienced growing deprofessionalism and politicization. He compares the impact of this evolution in both democratic societies and societies struggling to consolidate democratic institutions. Dismantling Democratic States cautions that our failure to acknowledge the role of an effective bureaucracy in building and preserving democratic political systems threatens the survival of democracy itself. 606 $aOrganizational change 606 $aAdministrative agencies$xReorganization 606 $aPrivatization 606 $aBureaucracy 606 $aDemocracy 608 $aElectronic books. 615 0$aOrganizational change. 615 0$aAdministrative agencies$xReorganization. 615 0$aPrivatization. 615 0$aBureaucracy. 615 0$aDemocracy. 676 $a321.8 700 $aSuleiman$b Ezra$01042737 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910453543703321 996 $aDismantling democratic states$92467190 997 $aUNINA LEADER 05552nam 2200721Ia 450 001 9911019347803321 005 20200520144314.0 010 $a9786612472060 010 $a9781282472068 010 $a1282472062 010 $a9780470748862 010 $a0470748869 010 $a9780470748855 010 $a0470748850 035 $a(CKB)2550000000002112 035 $a(EBL)477884 035 $a(OCoLC)463438682 035 $a(SSID)ssj0000335873 035 $a(PQKBManifestationID)11273401 035 $a(PQKBTitleCode)TC0000335873 035 $a(PQKBWorkID)10278286 035 $a(PQKB)10546062 035 $a(MiAaPQ)EBC477884 035 $a(PPN)143478532 035 $a(Perlego)2755382 035 $a(EXLCZ)992550000000002112 100 $a20090428d2009 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aClick chemistry for biotechnology and materials science /$fedited by Joerg Lahann 210 $aChichester, West Sussex $cWiley$d2009 215 $a1 online resource (433 p.) 300 $aDescription based upon print version of record. 311 08$a9780470699706 311 08$a0470699701 320 $aIncludes bibliographical references and index. 327 $aClick Chemistry for Biotechnologyand Materials Science; Contents; Preface; List of Contributors; Acknowledgments; 1 Click Chemistry: A Universal Ligation Strategy for Biotechnology and Materials Science; 1.1 Introduction; 1.2 Selected Examples of Click Reactions in Materials Science and Biotechnology; 1.3 Potential Limitations of Click Chemistry; 1.4 Conclusions; References; 2 Common Synthons for Click Chemistry in Biotechnology; 2.1 Introduction - Click Chemistry; 2.2 Peptides and Derivatives; 2.3 Peptoids; 2.4 Peptidic Dendrimers; 2.5 Oligonucleotides; 2.6 Carbohydrates; 2.7 Conclusion 327 $aReferences3 Copper-free Click Chemistry; 3.1 Introduction; 3.2 Bio-orthogonal Ligations; 3.2.1 Condensations of Ketones and Aldehydes with Heteroatom-bound Amines; 3.2.2 Staudinger Ligation of Phosphines and Azides; 3.2.3 Copper-free Azide-Alkyne Cycloadditions; 3.2.4 Bioorthogonal Ligations of Alkenes; 3.3 Applications of Copper-free Click Chemistries; 3.3.1 Activity-based Profiling of Enzymes; 3.3.2 Site-specific Labeling of Proteins; 3.3.3 Metabolic Labeling of Glycans; 3.3.4 Metabolic Targeting of Other Biomolecules with Chemical Reporters; 3.4 Summary and Outlook; References 327 $a4 Protein and Peptide Conjugation to Polymers and Surfaces Using Oxime Chemistry4.1 Introduction; 4.2 Protein/Peptide-Polymer Conjugates; 4.3 Immobilization of Proteins and Peptides on Surfaces; 4.4 Conclusions; References; 5 The Role of Click Chemistry in Polymer Synthesis; 5.1 Introduction; 5.2 Polymerization via CuAAC; 5.3 Post-polymerization Modification via Click Chemistry; 5.4 Polymer-Biomacromolecule Conjugation; 5.5 Functional Nanomaterials; 5.6 Summary and Outlook; References; 6 Blocks, Stars and Combs: Complex Macromolecular Architecture Polymers via Click Chemistry 327 $a6.1 Introduction6.2 Block Copolymers; 6.2.1 Preparing Polymers for Click Conjugations; 6.2.2 The Click Reaction: Methodologies and Isolation; 6.2.3 Polymer Characterization; 6.3 Star Polymers; 6.3.1 Star polymers An; 6.3.2 Dentritic Star Polymers; 6.4 Graft Copolymers; 6.4.1 'Grafting-to' Azide Main Chains; 6.4.2 'Grafting-to' Alkyne Main Chains; 6.4.3 Non-CuAAC Routes; 6.5 Concluding Remarks; References; 7 Click Chemistry on Supramolecular Materials; 7.1 Introduction; 7.2 Click Reactions on Rotaxanes, Cyclodextrines and Macrocycles; 7.2.1 Click with Rotaxanes; 7.2.2 Click on Cyclodextrines 327 $a7.2.3 Click on Macrocycles7.3 Click Reactions on DNA; 7.4 Click Reactions on Supramolecular Polymers; 7.5 Click Reactions on Membranes; 7.6 Click Reactions on Dendrimers; 7.7 Click Reactions on Gels and Networks; 7.8 Click Reactions on Self-assembled Monolayers; References; 8 Dendrimer Synthesis and Functionalization by Click Chemistry for Biomedical Applications; 8.1 Introduction; 8.2 Dendrimer Synthesis; 8.2.1 Divergent Synthesis; 8.2.2 Convergent Synthesis; 8.3 Dendrimer Functionalization; 8.4 Conclusions and Future Directions; References 327 $a9 Reversible Diels-Alder Cycloaddition for the Design of Multifunctional Network Polymers 330 $aMimicking natural biochemical processes, click chemistry is a modular approach to organic synthesis, joining together small chemical units quickly, efficiently and predictably. In contrast to complex traditional synthesis, click reactions offer high selectivity and yields, near-perfect reliability and exceptional tolerance towards a wide range of functional groups and reaction conditions. These 'spring loaded' reactions are achieved by using a high thermodynamic driving force, and are attracting tremendous attention throughout the chemical community. Originally introduced with the focus on dru 606 $aBiotechnology 606 $aMaterials science 606 $aCombinatorial chemistry 606 $aMacromolecules$xSynthesis 615 0$aBiotechnology. 615 0$aMaterials science. 615 0$aCombinatorial chemistry. 615 0$aMacromolecules$xSynthesis. 676 $a660.6 701 $aLahann$b Joerg$01839084 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911019347803321 996 $aClick chemistry for biotechnology and materials science$94418209 997 $aUNINA