LEADER 03242nam 2200589Ia 450 001 9910453066503321 005 20200520144314.0 010 $a1-281-96817-X 010 $a9786611968175 010 $a981-281-478-7 035 $a(CKB)1000000000554952 035 $a(EBL)1193653 035 $a(SSID)ssj0000301558 035 $a(PQKBManifestationID)12096924 035 $a(PQKBTitleCode)TC0000301558 035 $a(PQKBWorkID)10263559 035 $a(PQKB)11584129 035 $a(MiAaPQ)EBC1193653 035 $a(WSP)00006403 035 $a(Au-PeEL)EBL1193653 035 $a(CaPaEBR)ebr10688086 035 $a(CaONFJC)MIL196817 035 $a(OCoLC)318879610 035 $a(EXLCZ)991000000000554952 100 $a20090306d2008 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aLecture notes on computational structural biology$b[electronic resource] /$fZhijun Wu 210 $aSingapore ;$aHackensack, NJ $cWorld Scientific$dc2008 215 $a1 online resource (244 p.) 300 $aDescription based upon print version of record. 311 $a981-270-589-9 320 $aIncludes bibliographical references and index. 327 $a1. Introduction. 1.1. Protein structure. 1.2. Structure determination. 1.3. Dynamics simulation. 1.4. The myth of protein folding -- 2. X-ray crystallography computing. 2.1. The phase problem. 2.2. Least squares solutions. 2.3. Entropy maximization. 2.4. Indirect methods -- 3. NMR structure determination. 3.1. Nuclear magnetic resonance. 3.2. Distance geometry. 3.3. Distance-based modeling. 3.4. Structural analysis -- 4. Potential energy minimization. 4.1. Potential energy function. 4.2. Local optimization. 4.3. Global optimization. 4.4. Energy transformation -- 5. Molecular dynamics simulation. 5.1. Equations of motion. 5.2. Initial-value problem. 5.3. Boundary-value problem. 5.4. Normal mode analysis -- 6. Knowledge-based protein modeling. 6.1. Sequence/structural alignment. 6.2. Fold recognition/inverse folding. 6.3. Knowledge-based structural refinement. 6.4. Structural computing and beyond. 330 $aWhile the field of computational structural biology or structural bioinformatics is rapidly developing, there are few books with a relatively complete coverage of such diverse research subjects studied in the field as X-ray crystallography computing, NMR structure determination, potential energy minimization, dynamics simulation, and knowledge-based modeling. This book helps fill the gap by providing such a survey on all the related subjects. Comprising a collection of lecture notes for a computational structural biology course for the Program on Bioinformatics and Computational Biology at Iow 606 $aComputational biology 606 $aStructural bioinformatics 608 $aElectronic books. 615 0$aComputational biology. 615 0$aStructural bioinformatics. 676 $a572.80285 700 $aWu$b Zhijun$f1956-$0951797 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910453066503321 996 $aLecture notes on computational structural biology$92151602 997 $aUNINA LEADER 03647nam 2200661 a 450 001 9910452455303321 005 20200520144314.0 010 $a90-04-23267-2 024 7 $a10.1163/9789004232679 035 $a(CKB)2550000001103100 035 $a(EBL)1319091 035 $a(OCoLC)854521052 035 $a(SSID)ssj0000952960 035 $a(PQKBManifestationID)11602822 035 $a(PQKBTitleCode)TC0000952960 035 $a(PQKBWorkID)10909286 035 $a(PQKB)11756894 035 $a(MiAaPQ)EBC1319091 035 $a(nllekb)BRILL9789004232679 035 $a(PPN)184928354 035 $a(Au-PeEL)EBL1319091 035 $a(CaPaEBR)ebr10735404 035 $a(CaONFJC)MIL505606 035 $a(EXLCZ)992550000001103100 100 $a20130620d2013 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aAspects of sovereignty$b[electronic resource] $eSino-Swedish reflections /$fedited by Per Sevastik 210 $aLeiden $cMartinus Nijhoff Publishers$d2013 215 $a1 online resource (198 p.) 225 1 $aThe Raoul Wallenberg Institute human rights library,$x1388-3208 ;$vv. 42 300 $aDescription based upon print version of record. 300 $aIncludes index. 311 $a90-04-23266-4 311 $a1-299-74355-2 320 $aIncludes bibliographical references and index. 327 $aIntroduction / Per Sevastik -- Sovereignty's implications for China : then and now / Junwu Pan -- Some aspects on the effects of human rights law and its implications on international law / Per Sevastik -- Sovereignty and transnational investments / Par Hallstrom -- Regional integration and sovereignty : the sum is more than its parts? / Katrin Nyman-Metcalf -- Hong Kong's sub-sovereign status and its external relations / Simon Shen -- Intertwined sovereignties and the problem of legitimate opposition in the European Union / Sverker Gustavsson -- The horizontal state : states and agencies in a world without boundaries / Bo Wennstrom -- The end of state sovereignty? : from a Chinese perspective / Zewei Yang. 330 $aThe overall objective of this unique volume is to understand what effects globalisation has had on the traditional views of sovereignty, seen from a Chinese and European, primarily Swedish, perspective. Does the cultural-historical approach have any value in China today or is it only seen as political reminiscence with very little real effects in the wake of globalisation? What are the differences between different understandings of sovereignty in different parts of the world? How has the concept changed generally because of a different international structure, with for example regional integration gaining in importance not least in Europe? These are some of the underlying questions being addressed in this anthology. The authors are Chinese and Swedish scholars who offer reflections from the perspective of legal philosophy, public international law, international human rights law, economic law and international relations. 410 0$aRaoul Wallenberg Institute human rights library ;$vv. 42. 606 $aSovereignty 606 $aInternational law$zChina 606 $aInternational law$zSweden 608 $aElectronic books. 615 0$aSovereignty. 615 0$aInternational law 615 0$aInternational law 676 $a320.15 701 $aSevastik$b Per$0552526 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910452455303321 996 $aAspects of sovereignty$91939821 997 $aUNINA