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010   $a9786611733568
010   $a1-60750-265-8
010   $a600-00-0512-1
010   $a1-4356-2516-1
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100   $a20070924d2007      uy             0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 00$aOsteoarthritis, inflammation and degradation$b[electronic resource] $ea continuum /$fedited by Joseph A. Buckwalter, Martin Lotz and Jean-Franc?ois Stoltz
210   $aAmsterdam ;$aWashington, DC $cIOS Press$dc2007
215   $a1 online resource (316 p.)
225 1 $aBiomedical and health research,$x0929-6743 ;$vv. 70
300   $aDescription based upon print version of record.
311   $a1-58603-773-0 
320   $aIncludes bibliographical references and index.
327   $aTitle page; Preface; Acknowledgments and Contributors; Contents; Extra Cellular Stimuli; Signalling Mechanisms; Effectors and Different Pathways; Imaging and Clinical Applications; Author Index
330   $aOsteoarthritis is a major public health issue due to its impact in term of handicap. Moreover, ageing of the world population and outbreak of obesity in industrialized and non-industrialized countries will dramatically increase its incidence in the next years. Regarded as a multi-factorial disease, today mechanistic and inflammatory theories are no more opposed but, on the contrary, are framed within the same continuum: osteoarthritis, inflammation and degeneration.In order to collect major information in a benchmark book on the fundamental aspects of this disease, internationally well-known a
410  0$aBiomedical and health research ;$vv. 70.
606   $aBiochemical markers
606   $aOsteoarthritis
608   $aElectronic books.
615  0$aBiochemical markers.
615  0$aOsteoarthritis.
676   $a616.7/223007548
701   $aBuckwalter$b Joseph A$0868930
701   $aLotz$b Martin$g(Martin K.)$0731194
701   $aStoltz$b J. F$0868931
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910452455103321
996   $aOsteoarthritis, inflammation and degradation$91939820
997   $aUNINA