LEADER 03591nam 22006372 450 001 9910452279103321 005 20151005020622.0 010 $a1-107-33061-0 010 $a1-107-33622-8 010 $a1-107-32646-X 010 $a1-107-33456-X 010 $a1-107-33290-7 010 $a1-139-01877-9 010 $a1-107-33539-6 035 $a(CKB)2550000001108096 035 $a(EBL)1139553 035 $a(OCoLC)841487122 035 $a(SSID)ssj0000861042 035 $a(PQKBManifestationID)11475166 035 $a(PQKBTitleCode)TC0000861042 035 $a(PQKBWorkID)10913888 035 $a(PQKB)11470655 035 $a(UkCbUP)CR9781139018777 035 $a(MiAaPQ)EBC1139553 035 $a(Au-PeEL)EBL1139553 035 $a(CaPaEBR)ebr10740491 035 $a(CaONFJC)MIL508449 035 $a(EXLCZ)992550000001108096 100 $a20110216d2013|||| uy| 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aFed-batch cultures $eprinciples and applications of semi-batch bioreactors /$fHenry C. Lim, University of California, Irvine, Hwa Sung Shin, Inha University$b[electronic resource] 210 1$aCambridge :$cCambridge University Press,$d2013. 215 $a1 online resource (xvii, 457 pages) $cdigital, PDF file(s) 225 1 $aCambridge series in chemical engineering 300 $aTitle from publisher's bibliographic system (viewed on 05 Oct 2015). 311 $a0-521-51336-7 311 $a1-299-77198-X 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aIntroduction to fed-batch bioreactors -- Idealised reactors and fed-batch reactors -- Maximisation of reaction rates and fed-batch operation -- Phenomena that favour fed-batch operations -- Classification and characteristics of fed-batch cultures -- Models based on mass balance equations -- Non-equation-based models -- Experimental determination of specific rates -- Optimization via Pontryagin's maximum principle -- Computational techniques -- Optimization of single and multiple isothermal reactions -- Optimization of fed-batch cultures for cell mass production -- Optimization of fed-batch cultures for metabolites -- Simple, intuitive adaptive optimization -- Measurements, estimation and control -- Feasibility assessment and implementable feed rates. 330 $aMany, if not most, industrially important fermentation and bioreactor operations are carried out in fed-batch mode, producing a wide variety of products. In spite of this, there is no single book that deals with fed-batch operations. This is the first book that presents all the necessary background material regarding the 'what, why and how' of optimal and sub-optimal fed-batch operations. Numerous examples are provided to illustrate the application of optimal fed-batch cultures. This unique book, by world experts with decades of research and industrial experience, is a must for researchers and industrial practitioners of fed-batch processes (modeling, control and optimization) in biotechnology, fermentation, food, pharmaceuticals and waste treatment industries. 410 0$aCambridge series in chemical engineering. 606 $aBioreactors 615 0$aBioreactors. 676 $a660/.6 700 $aLim$b Henry C.$f1935-$01050702 702 $aShin$b Hwa Sung$f1974- 801 0$bUkCbUP 801 1$bUkCbUP 906 $aBOOK 912 $a9910452279103321 996 $aFed-batch cultures$92480725 997 $aUNINA