LEADER 03151nam 22006614a 450 001 9910451812703321 005 20200520144314.0 010 $a1-281-73047-5 010 $a9786611730475 010 $a0-300-12970-X 024 7 $a10.12987/9780300129700 035 $a(CKB)1000000000472014 035 $a(StDuBDS)AH23049610 035 $a(SSID)ssj0000233951 035 $a(PQKBManifestationID)11202524 035 $a(PQKBTitleCode)TC0000233951 035 $a(PQKBWorkID)10235606 035 $a(PQKB)10705938 035 $a(MiAaPQ)EBC3419998 035 $a(DE-B1597)484980 035 $a(OCoLC)952732441 035 $a(DE-B1597)9780300129700 035 $a(Au-PeEL)EBL3419998 035 $a(CaPaEBR)ebr10170024 035 $a(OCoLC)923589448 035 $a(EXLCZ)991000000000472014 100 $a20051114d2006 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt 182 $cc 183 $acr 200 10$aReconceiving the gene$b[electronic resource] $eSeymour Benzer's adventures in phage genetics /$fFrederic Lawrence Holmes ; edited by William C. Summers 210 $aNew Haven $cYale University Press$dc2006 215 $a1 online resource (352 p.) 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a0-300-11078-2 320 $aIncludes bibliographical references (p. [303]-329) and index. 327 $aClassical mendelian genetics -- Genetics and the phage biologists -- The physicist becomes a phage biologist -- To Paris and back -- Teaching and research at Purdue -- Entering the rII region -- Crossing into the fine structure -- Is gene a dirty word? -- The survival of the "gene". 330 $aThis book relates how, between 1954 and 1961, the biologist Seymour Benzer mapped the fine structure of the rII region of the genome of the bacterial virus known as phage T4. Benzer's accomplishments are widely recognized as a tipping point in mid-twentieth-century molecular biology when the nature of the gene was recast in molecular terms. More often than any other individual, he is considered to have led geneticists from the classical gene into the molecular age. Drawing on Benzer's remarkably complete record of his experiments, his correspondence, and published sources, this book reconstructs how the former physicist initiated his work in phage biology and achieved his landmark investigation. The account of Benzer's creativity as a researcher is a fascinating story that also reveals intriguing aspects common to the scientific enterprise. 606 $aGeneticists$zUnited States$vBiography 606 $aBacteriophages$xGenetics 606 $aViral genetics$xHistory 608 $aElectronic books. 615 0$aGeneticists 615 0$aBacteriophages$xGenetics. 615 0$aViral genetics$xHistory. 676 $a576.5092 676 $aB 700 $aHolmes$b Frederic Lawrence$0726772 701 $aSummers$b William C$01043501 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910451812703321 996 $aReconceiving the gene$92468520 997 $aUNINA