LEADER 04190oam 2200733I 450 001 9910451557703321 005 20200520144314.0 010 $a0-429-07777-7 010 $a1-4822-8342-5 010 $a1-280-07992-4 010 $a9786610079926 010 $a0-203-30429-2 024 7 $a10.1201/9781482283426 035 $a(CKB)1000000000334746 035 $a(EBL)181531 035 $a(OCoLC)475891948 035 $a(SSID)ssj0000284005 035 $a(PQKBManifestationID)11912567 035 $a(PQKBTitleCode)TC0000284005 035 $a(PQKBWorkID)10260961 035 $a(PQKB)10064770 035 $a(MiAaPQ)EBC181531 035 $a(Au-PeEL)EBL181531 035 $a(CaPaEBR)ebr10101069 035 $a(CaONFJC)MIL7992 035 $a(OCoLC)1000425491 035 $a(EXLCZ)991000000000334746 100 $a20180706d1998 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aSecretory systems and toxins /$fedited by Michal Linial, Alfonso Grasso and Philip Lazarovici 210 1$aAmsterdam :$cHarwood Academic Publishers,$d1998. 215 $a1 online resource (500 p.) 225 1 $aCellular and molecular mechanisms of toxin action,$x1026-4078 ;$vv. 2 300 $aDescription based upon print version of record. 311 $a0-203-35387-0 311 $a90-5702-335-0 320 $aIncludes bibliographical references and index. 327 $aBook Cover; Title; Contents; Preface to the Series; Preface; Contributors; Synaptic Vesicle Proteins: A Molecular Study; Synaptic Vesicle Proteins: A Genetic Approach; Dissection of the Secretory Machinery; Vesicular Trafficking on the Late Secretory Pathway in the Budding Yeast, S. Cerevisiae: Yeast as a Genetic Tool in Which to Explore Protein Export; Regulatory Roles for Lipids in Vesicle Trafficking and Secretion; Fusion Proteins and the Fusion Events; Tetanus Toxin as a Valuable Pharmacological Tool for Studying Polysialogangliosides in Neuronal Signal Transduction 327 $aMolecular Mechanisms of the Action of Clostridium Botulinum Type B Neurotoxin-Latrotoxin Receptors; Neurotoxins and Safety-Latches of the Secretory Process; Bacterial Neurotoxins in Invertebrates: Aplysia and the Deciphering of the Mode of Action of Clostridial Neurotoxins; Chromaffin Cells as a Secretory System: The Use of Neurotoxins; External Ions and -Latrotoxin Action; Botulinum Neurotoxins and their Substrates; Clostridial Neurotoxins as Enzymes: Structure and Function; Purification, Function and Selectivity in -Latrotoxin 327 $aNeurotoxins, Cytoskeletons and Calcium Channels: Functional Studies at Mammalian Synapses Formed in CultureThe Synapsins and Neurotransmission; Morphological Studies of the Secretory Machinery Using Neurotoxin Probes; Membrane Fusion Protein Annexin VII: A Ca2+-Activated GTPase Target for Mastoparan in Secreting Chromaffin Cells; Glossary; Index 330 $aThis volume deals with the relationships between toxins and one of the most fundamental processes in any living cell - the secretory cycle. The reader will find up-to-date information on secretion, generated by experts in this fast evolving field. In the last decade extensive molecular and cellular studies have exposed the molecular similarity among most known secretory systems. In this book secretion is discussed from its basic mode found in yeast up to its most sophisticated version in neurotransmitter release in nerve terminals. A comprehensive view on the mode of action of toxins which blo 410 0$aCellular and molecular mechanisms of toxin action ;$vv. 2. 606 $aSecretion 606 $aToxins 606 $aNeurotoxic agents 608 $aElectronic books. 615 0$aSecretion. 615 0$aToxins. 615 0$aNeurotoxic agents. 676 $a571.79 701 $aGrasso$b Alfonso$0100938 701 $aLazarovici$b Philip$099566 701 $aLinial$b Michal$0876795 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910451557703321 996 $aSecretory systems and toxins$91957979 997 $aUNINA