LEADER 03496nam 22006134a 450 001 9910451422703321 005 20200520144314.0 010 $a9786611160203 010 $a1-281-16020-2 010 $a0-19-152404-2 010 $a1-4356-0564-0 035 $a(CKB)1000000000411469 035 $a(EBL)430445 035 $a(OCoLC)609829946 035 $a(SSID)ssj0000145743 035 $a(PQKBManifestationID)11135059 035 $a(PQKBTitleCode)TC0000145743 035 $a(PQKBWorkID)10183135 035 $a(PQKB)11412176 035 $a(MiAaPQ)EBC430445 035 $a(Au-PeEL)EBL430445 035 $a(CaPaEBR)ebr10194236 035 $a(CaONFJC)MIL116020 035 $a(EXLCZ)991000000000411469 100 $a20060106d2006 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aEmbryonic stem cells$b[electronic resource] $ea practical approach /$fedited by Elena Notarianni, Martin J. Evans 210 $aOxford ;$aNew York $cOxford University Press$d2006 215 $a1 online resource (361 p.) 225 1 $aPractical approach series 300 $aDescription based upon print version of record. 311 $a0-19-855001-4 311 $a0-19-855000-6 320 $aIncludes bibliographical references and index. 327 $aProcedures for deriving ES cell lines from the mouse / Frances A. Brook -- Production of ES cell-derived mice / Yoko Kato and Yukio Tsunoda -- Generating animal models of human mitochondrial genetic disease using mouse ES cells / Grant R. MacGregor ... [et al.] -- Controlling the differentiation of mouse ES cells in vitro / Michael V. Wiles and Gabriele Proetzel -- In vitro differentiation of mouse ES cells into muscle cells / Yelena S. Tarasova [et al.] -- In vitro differentiation of mouse ES cells into haematopoietic cells / Osamu Ohneda and Masayuki Yamamoto -- Lineage selection and transplantation of mouse ES cell-derived neural precursors / Tanja Schmandt, Tamara Glaser and Oliver Bru?stle -- In vitro differentiation of mouse ES cells into pancreatic and hepatic cells / Przemyslaw Blyszczuk, Gabriela Kania and Anna M. Wobus -- Isolation and characterization of human ES cells / Martin F. Pera -- Differentiation of human ES cells / Sharon Gerecht-Nir and Joseph Itskovitz-Eldor -- ES cell lines from the cynomolgus monkey (Macaca fascicularis) / Hirofumi Suemori [et al.]. 330 $aThe groundbreaking isolation of embryonic stem cells (or 'ES cells') of the mouse in the early 1980's triggered a sustained expansion of global research into their exploitation. This led to the routine genetic engineering of the mouse and revolutionised our understanding of biological processes in the context of the whole animal. ES cell biology remains a crucial and growing area of research with far-reaching implications for developmental and comparative biology as well as for human health. This book serves as a primer to ES cells, their derivation and experimental manipulation. It contains a... 410 0$aPractical approach series. 606 $aEmbryonic stem cells 608 $aElectronic books. 615 0$aEmbryonic stem cells. 676 $a612.6/4 701 $aNotarianni$b Elena$0907388 701 $aEvans$b Martin J.$cProf.$0106630 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910451422703321 996 $aEmbryonic stem cells$92029844 997 $aUNINA