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101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
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183   $acr
200 12$aA means to an end $ethe biological basis of aging and death /$fWilliam R. Clark
210  1$aNew York ;$aOxford, [England] :$cOxford University Press,$d1999.
210  4$dİ1999
215   $a1 online resource (252 p.)
300   $aOriginally published: 1999.
311   $a0-19-512593-2 
311   $a0-19-515375-8 
320   $aIncludes bibliographical references and index.
327   $aContents; Acknowledgments; Introduction; 1. Aging, Senescence, and Lifespan; 2. The Nature of Cellular Senescence and Death; 3. The Evolution of Senescence and Death; 4. Of Embryos and Worms and Very Old Men: The Developmental Genetics of Senescence and Lifespan; 5. Human Genetic Diseases That Mimic the Aging Process; 6. Cycling to Senescence; 7. Replicative Immortality: Cancer and Aging; 8. Caloric Restriction and Maximum Lifespan; 9. With Every Breath We Take: Oxidative Stress and Cellular Senescence; 10. The Aging Brain; 11. A Conditional Benefit; Bibliography; Index
330   $aIn this work, the various theories of ageing are explained and assessed. The author presents case accounts about disorders that open windows on to the ageing process. The impacts of ageing on the brain and nervous system are given special attention, as are the effects of caloric restriction on maximum lifespan.
606   $aCells$xAging
606   $aApoptosis
608   $aElectronic books.
615  0$aCells$xAging.
615  0$aApoptosis.
676   $a612.6/7
700   $aClark$b William R.$f1938-$0262163
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910450265403321
996   $aA means to an end$92154661
997   $aUNINA