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010   $a9786610162215
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101 0 $aeng
135   $aur|||||||||||
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aHepatitis C virus $efrom laboratory to clinic /$fMark A. Feitelson$b[electronic resource]
210  1$aCambridge :$cCambridge University Press,$d2002.
215   $a1 online resource (xiv, 256 pages) $cdigital, PDF file(s)
300   $aTitle from publisher's bibliographic system (viewed on 05 Oct 2015).
311   $a0-521-79959-7 
320   $aIncludes bibliographical references (p. 177-247) and index.
327   $aCover; Half-title; Title; Copyright; Dedication; Contents; Preface; Foreword; Abbreviations; Part I Basic principles; Part II Recent advances; Part III Experimental approaches; Part IV Protocols and techniques; Part V Some outstanding questions and emerging areas for investigation; References; Index
330   $aHepatitis C infects 170 million people worldwide, and has been labelled the 'silent epidemic' as a result of its concealed attack on the liver. This multidisciplinary overview covers basic concepts related to the discovery of the virus, development of serological and nucleic acid tests to detect infection, the structure of the virus genome, generation of virus gene products, and proposed replication scheme. It then goes on to introduce the epidemiology, transmission, pathogenesis of infection, the development of hepatocellular carcinoma associated with chronic virus infection, and current strategies for treatment. The book then discusses advances in cell culture systems, animal models of infection, and emerging treatments and vaccine development. Through its coverage of basic science, clinical consequences, and methods of research, this integrated and accessible account will be of immense value to biomedical scientists and clinicians alike, and a useful introduction for all those studying the virus and its effects.
606   $aHepatitis C
606   $aHepatitis C virus
615  0$aHepatitis C.
615  0$aHepatitis C virus.
676   $a616.3/623
700   $aFeitelson$b Mark$01037718
801  0$bUkCbUP
801  1$bUkCbUP
906   $aBOOK
912   $a9910449972603321
996   $aHepatitis C virus$92458849
997   $aUNINA