LEADER 03543oam 22006014a 450 001 9910447051603321 005 20240506064136.0 010 $a9789461662453 010 $a9461662459 024 8 $ahttps://doi.org/10.11116/9789461663979 035 $a(CKB)3790000000535161 035 $a(OCoLC)1009361134 035 $a(MdBmJHUP)muse65839 035 $a(MiAaPQ)EBC5117834 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/89982 035 $a(ScCtBLL)3f2f761e-e6a0-42bb-b008-e85ba975260f 035 $a(oapen)doab89982 035 $a(EXLCZ)993790000000535161 100 $a20171103d2017 uy 0 101 0 $aeng 135 $aur|||||||nn|n 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aCold War Triangle$eHow Scientists in East and West Tamed HIV /$fRenilde Loeckx 210 $cLeuven University Press$d2017 210 1$aBaltimore, Maryland :$cProject Muse,$d2017 210 4$dİ2017 215 $a1 online resource (1 PDF (186 pages) :)$cportraits 300 $aIssued as part of book collections on Project MUSE. 311 08$a9789461663979 311 08$a9461663978 311 08$a9789462701137 311 08$a946270113X 320 $aIncludes bibliographical references (pages 175-180) and index. 327 $aIntroduction -- I. Leuven : a hotbed for antiviral research -- II. Behind the Iron Curtain -- III. Strange bedfellows : a Czech chemist and a Flemish virologist -- IV. The sixties in Leuven and Prague -- V. Enzymes : the secret of life as chemistry -- VI. From interferon to nucleosides -- VII. Breaking away from interferon -- VIII. The first antiviral drugs -- IX. Aids emerges in the shadow of the Cold War -- X. From passivity to action -- XI. First attempts to halt the epidemic -- XII. Finding the best therapy : the one-a-day-pill -- Epilogue : of scientists and crusaders. 330 $aThe extraordinary story of scientists in East and West combatting HIV. A small group of scientists were doggedly working in the field of antiviral treatments when the AIDS epidemic struck. Faced with one of the grand challenges of modern biology of the twentieth century, scientists worked across the political divide of the Cold War to produce a new class of antivirals. Their molecules were developed by a Californian start-up together with teams of scientists at the Rega Institute of KU Leuven and the Institute of Organic Chemistry and Biochemistry (IOCB) of the Academy of Sciences in Prague. These molecules became the cornerstone of the blockbuster drugs now used to combat and prevent HIV. Cold War Triangle gives an insight into the human face of science as it recounts the extraordinary story of scientists in East and West who overcame ideological barriers and worked together for the benefit of humanity. 606 $aAIDS (Disease)$xResearch$xPolitical aspects 606 $aHIV infections$xResearch$xPolitical aspects 606 $aAIDS (Disease)$xInternational cooperation 606 $aHIV infections$xInternational cooperation 615 0$aAIDS (Disease)$xResearch$xPolitical aspects. 615 0$aHIV infections$xResearch$xPolitical aspects. 615 0$aAIDS (Disease)$xInternational cooperation. 615 0$aHIV infections$xInternational cooperation. 676 $a616.9792 700 $aLoeckx$b Renilde$01025911 801 0$bMdBmJHUP 801 1$bMdBmJHUP 906 $aBOOK 912 $a9910447051603321 996 $aCold War Triangle$92440009 997 $aUNINA