LEADER 03901nam 22005654a 450 001 9910446344103321 005 20200520144314.0 010 $a1-280-73550-3 010 $a9786610735501 010 $a1-84593-039-8 035 $a(CKB)1000000000344585 035 $a(EBL)289441 035 $a(OCoLC)133159509 035 $a(SSID)ssj0000217996 035 $a(PQKBManifestationID)11181558 035 $a(PQKBTitleCode)TC0000217996 035 $a(PQKBWorkID)10213222 035 $a(PQKB)11151728 035 $a(MiAaPQ)EBC289441 035 $a(Au-PeEL)EBL289441 035 $a(CaPaEBR)ebr10157984 035 $a(EXLCZ)991000000000344585 100 $a20050610d2006 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aParasitic flatworms $emolecular biology, biochemistry, immunology and physiology /$fedited by Aaron G. Maule and Nikki J. Marks 205 $a1st ed. 210 $aWallingford, UK ;$aCambridge, MA $cCABI$dc2006 215 $a1 online resource (468 p.) 300 $aDescription based upon print version of record. 311 $a0-85199-027-4 320 $aIncludes bibliographical references and index. 327 $aThe evolution of parasitism in flatworms / D.T.J. Littlewood -- Genomes and genomics of parasitic flatworms / D.A. Johnston -- Genetic discrimination of echinococcus species and strains / D.P. McManus -- Ribosomal DNA variation in parasitic flatworms / D. Blair -- Genetic studies on monogeneans with emphasis on Gyrodactylus / C.O. Cunningham and I. Matejusova -- The schistosome transcriptome / S. Verjovski-Almeida and R. DeMarco -- Transgenic flatworms / C.G. Grevelding -- Immunobiology of schistosomes / S.G. Forrester and E.J. Pearce -- Cestode infection : immunological considerations from host and tapeworm perspectives / D.M. McKay and R.A. Webb -- Signal transduction at the host-parasite interface / T.P. Yoshino, J.J. Vermeire and J.E. Humphries -- 327 $aParasite effects on the snail host transcriptome / M. Knight and N. Raghavan -- Developments in the chemotherapy of parasitic flatworms / G.C. Coles -- Drug resistance in schistosomes / T.A. Day and S. Botros -- Praziquantel : mechanism of action / R.M. Greenberg -- Cestode vaccine development / M.W. Lightowlers -- The development of a schistosome vaccine / R.A. Wilson and P.S. Coulson -- Flatworm parasite proteomics / R.M. Morphew, J. Barrett and P.M. Brophy -- Proteases in trematode biology / J.P. Dalton, C.R. Caffrey, M. Sajid, C. Stack, S. Donnelly, A. Loukas, T. Don, J. McKerrow, D.W. Halton and P.J. Brindley -- Signalling molecules and nerve-muscle function / A.G. Maule, N.J. Marks and T.A. Day -- Unusual aspects of metabolism in flatworm parasites / A.G.M. Tielens and J.J. van Hellemond -- Glycoconjugate structures / M. Wuhrer and R. Geyer -- Gene silencing in flatworms using RNA interference / P.J. Skelly. 330 $aThis book examines recent research into the molecular biology, genomics and transcriptomics of, and novel control strategies for, flatworm parasites. These include Cestodes (tapeworms) and Trematodes (flukes, schistosomes etc), which are the cause of a number of diseases of medical and veterinary importance. The book explores three main areas: phylogeny, genetics and transcriptomes; immunobiology, host-parasite interaction and control; and protein function, metabolism and physiology. Where appropriate, comparisons are made between different parasitic flatworms and between parasitic and free-li 606 $aPlatyhelminthes 615 0$aPlatyhelminthes. 676 $a616.9/62 701 $aMaule$b Aaron G$0988104 701 $aMarks$b Nikki J$0988105 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910446344103321 996 $aParasitic flatworms$92259526 997 $aUNINA