LEADER 02818nam 2200589Ia 450 001 9910446318603321 005 20200520144314.0 010 $a1-282-89349-1 010 $a9786612893490 010 $a1-84593-694-9 035 $a(CKB)3130000000000185 035 $a(EBL)617544 035 $a(SSID)ssj0000411939 035 $a(PQKBManifestationID)11250332 035 $a(PQKBTitleCode)TC0000411939 035 $a(PQKBWorkID)10366304 035 $a(PQKB)11123898 035 $a(MiAaPQ)EBC617544 035 $a(Au-PeEL)EBL617544 035 $a(CaPaEBR)ebr10426601 035 $a(CaONFJC)MIL289349 035 $a(OCoLC)688480203 035 $a(EXLCZ)993130000000000185 100 $a20100419d2010 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aAntimicrobial peptides $ediscovery, design, and novel therapeutic strategies /$fedited by Guangshun Wang 205 $a18th ed. 210 $aWallingford, Oxfordshire, UK $cCABI$dc2010 215 $a1 online resource (xvii, 230 pages) $cillustrations 225 1 $aAdvances in molecular and cellular microbiology ;$v18 311 0 $a1-84593-657-4 320 $aIncludes bibliographical references and index. 327 $aContents; Contributors; Preface; Introduction; PART I: NATURAL ANTIMICROBIAL PEPTIDES: NOMENCLATURE, CLASSIFICATION AND INTERESTING TEMPLATES FOR PEPTIDE ENGINEERING; PART II: EXPANDING THE PEPTIDE SPACE: PREDICTION METHODS, DESIGN STRATEGIES AND PEPTIDOMIMETICS; PART III: BIOPHYSICS, STRUCTURAL BIOLOGY AND MECHANISM OF ACTION OF ANTIMICROBIAL PEPTIDES; PART IV: NOVEL THERAPEUTIC STRATEGIES TO BOLSTER HOST DEFENCE; Index 330 $aAntimicrobial Peptides (AMPs) are an organism's built-in defence molecules that have attracted extensive research attention worldwide. Harnessing and creating them synthetically has the potential to help overcome increasing antibiotic resistance in many pathogens. In addition to covering the current advances in AMP research, this volume examines new technologies such as bioinformatics, combinatorial libraries, high-throughput screening, peptidomimetics, biophysics, and structural biology. This volume also describes new methods and strategies for AMP prediction, design, and applications that ov 410 0$aAdvances in molecular and cellular microbiology ;$v18. 606 $aPeptide antibiotics 606 $aPharmaceutical chemistry 615 0$aPeptide antibiotics. 615 0$aPharmaceutical chemistry. 676 $a615/.1 701 $aWang$b Guangshun$0854935 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910446318603321 996 $aAntimicrobial peptides$91909062 997 $aUNINA