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001 9910444254903321
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010   $a981-15-4501-4
024 7 $a10.1007/978-981-15-4501-6
035   $a(CKB)4100000011763211
035   $a(DE-He213)978-981-15-4501-6
035   $a(EXLCZ)994100000011763211
100   $a20201126d2020      u|             0
101 0 $aeng
135   $aurnn#008mamaa
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aHandbook of Oxidative Stress in Cancer: Mechanistic Aspects$b[electronic resource] /$fedited by Sajal Chakraborti, Bimal K Ray, Sushanta Roychowdhury
210  1$aSingapore :$cSpringer Singapore :$cImprint: Springer,$d2020.
215   $a1 online resource (X, 1690 p. 20 illus., 10 illus. in color.)
330   $aThis comprehensive, up-to-date reference work compiles the scientific research on the relationship between various forms of cancer and reactive oxygen species (ROS). It is well known that ROS play a key role in the various steps leading to malignancy, this includes increase in DNA mutation rates. The book brings together exciting reviews, written by leading experts all over the world. The book is divided into four broad sections. Each section describes the role of oxidative stress and underlying mechanisms and pathways, at various stages of cancer, including its role in carcinogenesis, cancer progression and metastasis. Further, the book describes how the reactive oxygen species (ROS) modulate gene expression and signal transduction pathways in cancer. One section of the book is also dedicated to the therapeutics in ROS-induced cancer. It discusses the ways to interfere with the cancer progression, and design anti-cancer drugs. The book provides an integrated approach for better understanding of the development phases of oxidative stress-induced cancers, and the current perspectives about therapeutics of cancers. It is a highly resourceful book and would be extremely important to clinicians, students and researchers in the field of cancer genetics, therapeutics and oncology. .
606   $aCancer research
606   $aGenetics
606   $aCancer Research$3https://scigraph.springernature.com/ontologies/product-market-codes/B11001
606   $aGenetics and Genomics$3https://scigraph.springernature.com/ontologies/product-market-codes/L32000
606   $aEstrès oxidatiu$2thub
606   $aCàncer$2thub
606   $aOxigen actiu$2thub
608   $aLlibres electrònics$2thub
615  0$aCancer research.
615  0$aGenetics.
615 14$aCancer Research.
615 24$aGenetics and Genomics.
615  7$aEstrès oxidatiu
615  7$aCàncer
615  7$aOxigen actiu
676   $a614.5999
702   $aChakraborti$b Sajal$4edt$4http://id.loc.gov/vocabulary/relators/edt
702   $aRay$b Bimal K$4edt$4http://id.loc.gov/vocabulary/relators/edt
702   $aRoychowdhury$b Sushanta$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910444254903321
996   $aHandbook of Oxidative Stress in Cancer$92930722
997   $aUNINA