LEADER 07468 am 22007333u 450 001 9910337530503321 005 20230125193337.0 010 $a3-030-02278-1 024 7 $a10.1007/978-3-030-02278-5 035 $a(CKB)4100000007205024 035 $a(DE-He213)978-3-030-02278-5 035 $a(MiAaPQ)EBC5919513 035 $a(Au-PeEL)EBL5919513 035 $a(OCoLC)1132418197 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/30061 035 $a(PPN)235231657 035 $a(EXLCZ)994100000007205024 100 $a20181212d2019 u| 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 14$aThe EBMT Handbook$b[electronic resource] $eHematopoietic Stem Cell Transplantation and Cellular Therapies /$fedited by Enric Carreras, Carlo Dufour, Mohamad Mohty, Nicolaus Kröger 205 $a7th ed. 2019. 210 $aCham$cSpringer Nature$d2019 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2019. 215 $a1 online resource (XL, 702 p. 56 illus., 38 illus. in color.) 311 $a3-030-02277-3 327 $aPart 1. Introduction -- 1. HSCT: Historical perspective -- 2. The EBMT: History, present and future -- 3. The role of unrelated donor registries in HSCT -- 4. The HSCT Unit -- 5. JACIE accreditation of HSCT programs -- 6. Statistical methods in HSCT and Cellular Therapies -- Part 2. Biological aspects -- 7. Biological properties of HSC: scientific basis for HSCT -- 8. Biological properties of cells other than HSC -- 9. Histocompatibility -- 10. Clinical & biological concepts for mastering Immune reconstitution after HSCT: towards practical guidelines and greater harmonization -- Part 3. Methodology and clinical aspects -- 11. Evaluation and counselling of candidates -- 12. Donor selection for adults and pediatrics -- 13. Conditioning -- 14. Bone marrow harvesting for HSCT -- 15. Mobilization and collection of HSC -- 16. Collection of HSC in children -- 17. Processing, cryopreserving, and controlling the quality of HSCs -- 18. Procurement and management of cord blood -- 19. Graft manipulation -- 20. Documentation of engraftment and chimerism after HSCT -- 21. Short and long-term controls after HSCT -- Part 4. General management of the patient -- 22. Vascular access -- 23. Transfusion support -- 24. Nutritional support -- 25. GVHD prophylaxis (immunosuppression) -- 26. Management ATG (SIRS) -- 27. Infections control and isolation procedures -- 28. General management of the patient; Specific aspects of children -- 29. Vaccinations -- 30. Psychological morbidity and support -- 31. Clinical relevant drug interactions in HSCT -- 32. Role of nursing in HSCT -- 33. Ethical issues in HSCT -- 34. Quality of life assessment after HSCT for pediatric and adults -- Part 5. HSCT complications and management -- 35. Neutropenic fever -- 36. Bacterial infections -- 37. Invasive fungal infections -- 38. Viral infections -- 39. Other life-threatening infections -- 40. Bleeding and thrombotic complications -- 41. Graft failure -- 42. Early complications of endothelial origin -- 43. Acute Graft-versus-Host Disease -- 44. Chronic Graft-versus-Host Disease -- 45. Post-transplant lymphoproliferative syndromes -- 46. Iron overload -- 47. Secondary neoplasia (other than PTLPS) -- Part 6. Specific organ complications -- 48. Ocular and oral complications -- 49. Hepatic complications -- 50. Gastrointestinal complications -- 51. Hemorrhagic cystitis and renal dysfunction -- 52. Non-infectious pulmonary complications -- 53. Neurological complications -- 54. Skin, hair and musculoskeletal complications -- 55. Cardiovascular diseases and metabolic syndrome -- 56. Endocrine disorders, fertility and sexual health -- Part 7. Prevention and management of relapse -- 57. Monitoring MRD in ALL and AML -- 58. Preventing/treating relapse with drugs -- 59. Delayed transfer of immune cells, or the art of Donor Lymphocyte Infusion -- 60. Cellular therapy with engineered T cells, efficacy and side effects -- 61. Mechanisms of Immune resistance -- 62. Regulatory Aspects of ATMP versus minimally manipulated immune cells -- Part 8. Specific modalities of HSCT and management -- 63. At-home HSCT -- 64. Umbilical cord blood transplantation in children and adults -- 65. Haploidentical HSCT -- 66. Photopheresis in adults and pediatrics -- 67. Overweight and obese patients -- 68. HSCT in elderly patients -- Part 9. Indications and results -- 69. Acute Myeloid Leukemia in adults -- 70. Acute Myeloid Leukemia in children -- 71. Acute Lymphoblastic Leukemia in adults -- 72. Acute lymphoblastic leukemia in children and adolescents -- 73. Myelodysplastic syndromes -- 74. Pediatric MDS including Refractory Cytopenia and Juvenile Myelomonocytic Leukemia -- 75. Myelodysplastic/myeloproliferative neoplasms -- 76. Myeloproliferative neoplasms -- 77. Severe aplastic anemia and PNH -- 78. Fanconi anemia and other hereditary Bone Marrow Failure syndromes -- 79. Hemoglobinopathies (Sickle Cell Disease and Thalassemia) -- 80. Multiple myeloma -- 81. Systemic light chain amyloidosis -- 82. POEMS syndrome and disease produced by other monoclonal immunoglobulins -- 83. Follicular lymphoma -- 84. Chronic lymphocytic leukemia -- 85. Diffuse large B cell lymphoma -- 86. Mantle cell lymphoma -- 87. Other T- and B-aggressive lymphomas and lymphomas associated to HIV -- 88. Classical Hodgkin?s lymphoma -- 89. Primary immunodeficiencies -- 90. Inborn error of metabolism and osteopetrosis -- 91. Autoimmune disease -- 92. Solid tumors. 330 $aThis Open Access 7th edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field. Discussing all types of stem cell and bone marrow transplantation, including haplo-identical stem cell and cord blood transplantation, it also covers the indications for transplantation, the management of early and late complications as well as the new and rapidly evolving field of cellular therapies. 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The central themes of this book are- required skill formation, upskilling of the workers, and their interaction with technological change in lieu of a deficient educational system and its implications. An empirical investigation of the causes and consequences of low skill and technology indicators using a primary survey at macro and micro levels is undertaken. This is followed by an examination of the interaction between the low skill and technology indicators, the relationships between skill, upskilling and technology indicators, skills mismatch, the uses and impacts of ICT and differences at firm as well as industry level and knowledge transfer effects. A set of recommendations towards the need for implementation of consistent policies, increasing incentives and collaboration between public and private institutions completes the book. 606 $aEconomic development$zSudan 606 $aResearch$zSudan 606 $aTechnology$zSudan 615 0$aEconomic development 615 0$aResearch 615 0$aTechnology 676 $a361.3/2 676 $a361.32 700 $aNour$b Samia Mohamed$0866716 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910438073003321 996 $aTechnological Change and Skill Development in Sudan$92536711 997 $aUNINA