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010   $a9786613925138
010   $a3-7091-1125-0
024 7 $a10.1007/978-3-7091-1125-3
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035   $a(EBL)973350
035   $a(OCoLC)809934165
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035   $a(PQKBTitleCode)TC0000737123
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035   $a(DE-He213)978-3-7091-1125-3
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100   $a20120727d2013      uy         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 00$aDrug resistance in leishmania parasites $econsequences, molecular mechanisms and possible treatments /$fAlicia Ponte-Sucre, Emilia Diaz, Maritza Padron-Nieves, editors
205   $a1st ed. 2013.
210   $aNew York $cSpringer$d2013
215   $a1 online resource (457 p.)
300   $aDescription based upon print version of record.
311   $a3-7091-1706-2 
311   $a3-7091-0238-3 
320   $aIncludes bibliographical references and index.
327   $apt. 1. Determinant features in leishmaniasis -- pt. 2. Leishmania and the immune system -- pt. 3. Challenges in the diagnosis, treatment and control of leishmaniasis in times of drug resistance -- pt. 4. Molecular features of drug-resistant leishmania -- pt. 5. Pharmacology and chemotherapy of leishmaniasis -- pt. 6. Strategies to circumvent drug resistance in leishmania.
330   $aOne of the main problems concerning therapeutic tools for the treatment of parasitic diseases, including leishmaniasis, is that some field parasites are naturally resistant to the classical drugs; additionally, current therapies may select parasites prone to be resistant to the applied drugs. These features are (at least partially) responsible for the disappointing persistence of the disease and resultant deaths worldwide. This book provides a comprehensive view of the pathology of the disease itself, and of parasitic drug resistance, its molecular basis, consequences and possible treatments. Scientists both from academic fields and from the industry involved in biomedical research and drug design, will find in this book a valuable and fundamental guide that conveys the knowledge needed to understand and to improve the success in combating this disease worldwide.
606   $aLeishmania
606   $aParasites
615  0$aLeishmania.
615  0$aParasites.
676   $a616.9
676   $a616.9/364
701   $aDiaz$b Emilia$01755275
701   $aPadron-Nieves$b Maritza$01755276
701   $aPonte-Sucre$b Alicia$01755277
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910438022303321
996   $aDrug resistance in leishmania parasites$94192003
997   $aUNINA