LEADER 03195nam  2200601 a 450 
001 9910438019503321
005 20200520144314.0
010   $a1-283-91195-7
010   $a2-8178-0343-4
024 7 $a10.1007/978-2-8178-0343-2
035   $a(CKB)2670000000308967
035   $a(EBL)973140
035   $a(OCoLC)823382873
035   $a(SSID)ssj0000811607
035   $a(PQKBManifestationID)11463071
035   $a(PQKBTitleCode)TC0000811607
035   $a(PQKBWorkID)10850923
035   $a(PQKB)11095981
035   $a(DE-He213)978-2-8178-0343-2
035   $a(MiAaPQ)EBC973140
035   $a(PPN)168306816
035   $a(EXLCZ)992670000000308967
100   $a20121215d2013      uy         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 00$aPhysiology and physiopathology of adipose tissue /$fJean-Philippe Bastard, Bruno Feve, editors
205   $a1st ed. 2013.
210   $aParis $cSpringer$d2013
215   $a1 online resource (431 p.)
300   $aDescription based upon print version of record.
311   $a2-8178-0512-7 
311   $a2-8178-0342-6 
320   $aIncludes bibliographical references and index.
327   $apt. I. Adipose tissue development -- pt. II. Adipose tissue metabolic functions -- pt. III. Endocrine functions of adipocyte -- pt. IV. Pathology of adipose tissue.
330   $aThe scientific advances in the physiology and pathophysiology of adipose tissue over the last two decades have been considerable. Today, the cellular and molecular mechanisms of adipogenesis are well known. In addition, adipose tissue is now recognized as a real endocrine organ that produces hormones such as the leptin acting to regulate food intake and energy balance in the central nervous system, a finding that has completely revolutionized the paradigm of energy homeostasis. Other adipokines have now been described and these molecules are taking on increasing importance in physiology and pathophysiology. Moreover, numerous works have shown that in obesity, but also in cases of lipodystophy, adipose tissue was the site of a local low-grade inflammation that involves immune cells such as macrophages and certain populations of lymphocytes. This new information is an important step in the pathophysiology of both obesity and related metabolic and cardiovascular complications. Finally, it is a unique and original work focusing on adipose tissue, covering biology and pathology by investigating aspects of molecular and cellular biology, general, metabolic, genetic and genomic biochemistry.
606   $aAdipose tissues$xPhysiology
606   $aAdipose tissues$xPathophysiology
615  0$aAdipose tissues$xPhysiology.
615  0$aAdipose tissues$xPathophysiology.
676   $a571.57
701   $aBastard$b Jean-Philippe$01757539
701   $aFeve$b Bruno$01757540
712 02$aAssociation francise d'etude et de recherche sur l'obe?site?.
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910438019503321
996   $aPhysiology and physiopathology of adipose tissue$94195420
997   $aUNINA