LEADER 01216nam 2200385Ia 450 001 996392906803316 005 20221107205844.0 035 $a(CKB)3360000000358168 035 $a(EEBO)2240889129 035 $a(OCoLC)226372823 035 $a(EXLCZ)993360000000358168 100 $a20080429d1577 uy 0 101 0 $adut 135 $aurbn||||a|bb| 200 10$aEpistolae HN$b[electronic resource] $eDe Vornompste Epistelen HN, die he dorch den Hilligen geist der Lieften .. 210 $a[S.l. $cs.n.]$d1577 215 $a[1]+ p. $cill 300 $aHN = Hendrik Niclaes. 300 $aFragment; consists of t.p. only. 300 $aPrinter's device on t.p. 300 $aReproduction of original in: British Library. 330 $aeebo-0018 606 $aEpistolaries$vEarly works to 1800 606 $aPrinters' marks$vSpecimens$vEarly works to 1800 608 $aPrinters' marks$y16th century. 608 $aTitle pages$y16th century. 615 0$aEpistolaries 615 0$aPrinters' marks 700 $aNiclaes$b Hendrik$f1502?-1580?$01003056 801 0$bUMI 801 1$bUMI 906 $aBOOK 912 $a996392906803316 996 $aEpistolae HN$92344303 997 $aUNISA LEADER 03259nam 2200553Ia 450 001 9910438014003321 005 20251116210339.0 010 $a1-4471-4438-4 024 7 $a10.1007/978-1-4471-4438-0 035 $a(CKB)3280000000020506 035 $a(OCoLC)843383940 035 $a(CaPaEBR)ebrary10699676 035 $a(SSID)ssj0000904275 035 $a(PQKBManifestationID)11480459 035 $a(PQKBTitleCode)TC0000904275 035 $a(PQKBWorkID)10920102 035 $a(PQKB)10440145 035 $a(DE-He213)978-1-4471-4438-0 035 $a(MiAaPQ)EBC1698424 035 $a(PPN)170486877 035 $a(EXLCZ)993280000000020506 100 $a20130522d2013 uy 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt 182 $cc 183 $acr 200 10$a3d histology evaluation of dermatologic surgery /$fHelmut Breuninger, Patrick Adam 205 $a1st ed. 2013. 210 $aLondon ;$aNew York $cSpringer$dc2013 215 $a1 online resource (144 p.) 300 $aBibliographic Level Mode of Issuance: Monograph 311 08$a1-4471-4437-6 320 $aIncludes bibliographical references and index. 330 $aBoth surgical skill and histological preparation and evaluation are important for successful treatment of various malignant skin tumors. In addition, good knowledge of local patterns of infiltration is required to achieve complete excision. All tumors may show an irregular, often asymmetric, mainly horizontal subclinical infiltration with a wide extent. When deep infiltrations are present, they are also often asymmetric and hard to determine before excision. Until recently these tumor outgrowths have only been detectable using histologic evaluation, but 3D histology is highly sensitive and can detect even very small tumor infiltrations. Very narrow margins can thus be taken for excision, which helps spare healthy skin as only a subsequently targeted re-excision will be necessary to remove all of the asymmetric tumor infiltrations. Therefore the resulting defect will be as small as possible and as large as necessary, and can be adapted to the requirements for aesthetic surgical defect closure. 3D Histology Evaluation of Dermatologic Surgery compares the most commonly used methods in order to give the reader a graphical overview of the current state-of-the-art. The basic principles of various surgical methods and histological workups of the complete 3D tumor margins are described and extensively illustrated to allow better understanding. Furthermore, more complex treatments of larger tumors are also included. Therefore, this book will be vital for all involved in the management of these patients, including practicing and trainee dermatologists, ENT, plastic and facial-surgeons, pathologists and oncologists. 606 $aSkin$xSurgery 606 $aHistology$xTechnique 615 0$aSkin$xSurgery. 615 0$aHistology$xTechnique. 676 $a616.5 700 $aBreuninger$b Helmut$0892290 701 $aAdam$b Patrick$0692811 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910438014003321 996 $a3d histology evaluation of dermatologic surgery$94185123 997 $aUNINA