LEADER 03428nam 2200601 a 450 001 9910438009603321 005 20200520144314.0 010 $a1-283-84921-6 010 $a1-62703-170-7 024 7 $a10.1007/978-1-62703-170-7 035 $a(CKB)2670000000278656 035 $a(EBL)1030376 035 $a(OCoLC)821618016 035 $a(SSID)ssj0000797702 035 $a(PQKBManifestationID)11484462 035 $a(PQKBTitleCode)TC0000797702 035 $a(PQKBWorkID)10738289 035 $a(PQKB)10907379 035 $a(DE-He213)978-1-62703-170-7 035 $a(MiAaPQ)EBC1030376 035 $a(PPN)168306018 035 $a(EXLCZ)992670000000278656 100 $a20121129d2013 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aT-cell lymphomas /$fFrancine Foss, editor 205 $a1st ed. 2013. 210 $aNew York $cHumana Press$d2013 215 $a1 online resource (347 p.) 225 0$aContemporary hematology 300 $aDescription based upon print version of record. 311 $a1-62703-169-3 320 $aIncludes bibliographical references and index. 327 $aClassification of the T-cell lymphomas -- Epidemiology, prognosis and outcomes for aggressive T-cell lymphomas -- Molecular pathogenesis of T-cell lymphoma -- HTLV-1 associated T-cell diseases -- The NK/T cell lymphomas -- CD30 positive T-cell lymphomas -- Extranodal T-cell lymphomas -- Nodal T-cell lymphomas -- The T-cell leukemias -- Chemotherapy and Bone Marrow Transplantation -- Antibodies and Targeted Therapies -- Novel agents for T-cell lymphomas -- Immune Therapies in T-cell lymphoma. 330 $aThe mature T and NK cell lymphomas are rare, comprising approximately 10% of all malignant lymphomas. The incidence of T-cell lymphoma is variable around the world, with a higher incidence compared to B-cell lymphomas in the Asian basin. While the overall incidence of B-cell lymphomas has begun to decline in the United States, the incidence of T-cell lymphomas continues to rise. Over the last decade, a number of novel agents have been developed which target T-cell lymphomas and studies have identified novel genes and pathways associated with lymphomagenesis in T-cells.   This comprehensive volume examines the clinical and biological aspects of the T-cell lymphoproliferative disorders in adults and children. The book includes an overview of both the cutaneous and the systemic T-cell malignancies and addresses the classification of T-cell lymphomas, the clinical features of each subtype, and the relevant molecular and genetic studies. Clinical outcomes and treatment strategies are discussed with an emphasis on the development of novel biological and targeted therapies. An outstanding resource for hematologists and oncologists, this book gathers insights from experts in the field and provides the most up-to-date information on all of the T-cell lymphoma subgroups and current and emerging therapies. 410 0$aContemporary Hematology 606 $aLymphomas 606 $aT cells 615 0$aLymphomas. 615 0$aT cells. 676 $a616.99 676 $a616.99446 701 $aFoss$b Francine$01761329 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910438009603321 996 $aT-cell lymphomas$94200686 997 $aUNINA