LEADER 03574nam 22006255 450 001 9910438005303321 005 20250708144732.0 010 $a1-299-33623-X 010 $a1-4471-4171-7 024 7 $a10.1007/978-1-4471-4171-6 035 $a(CKB)2670000000336348 035 $a(EBL)1081712 035 $a(OCoLC)828794667 035 $a(SSID)ssj0000879059 035 $a(PQKBManifestationID)11475039 035 $a(PQKBTitleCode)TC0000879059 035 $a(PQKBWorkID)10837467 035 $a(PQKB)10906131 035 $a(DE-He213)978-1-4471-4171-6 035 $a(MiAaPQ)EBC1081712 035 $a(PPN)168292823 035 $a(EXLCZ)992670000000336348 100 $a20130220d2013 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aHuman Fetal Tissue Transplantation /$fedited by Niranjan Bhattacharya, Phillip Stubblefield 205 $a1st ed. 2013. 210 1$aLondon :$cSpringer London :$cImprint: Springer,$d2013. 215 $a1 online resource (466 p.) 300 $aDescription based upon print version of record. 311 08$a1-4471-4170-9 320 $aIncludes bibliographical references and index. 327 $aPart I The ideas behind this book -- Part II Basic Science and the unique aspect of fetal growth and maturation -- Part III Fetal Cell transplant experiments in animal and human systems -- Part IV Fetal tissue transplant experiments in animal and human systems -- Part V Fetal Organ transplant experiments in animal and human systems -- Part VI Biobanking -- Ethics of fetal tissue transplant. 330 $aOver the past decade there have been major advances in the field of regenerative medicine with the promise to bring to reality, cures for debilitating diseases such as diabetes, heart failure, and Parkinson?s disease. Cellular products from a variety of sources are being evaluated for their ability to replace damaged tissue. Fetal tissues consist of stem cells and progenitor cells which have undergone initial commitment with varying states of differentiation. Stem cells from fetal tissues may also have a greater proliferative potential than their adult counterparts. In addition, fetal derived stem and progenitor cells are immunologically naive and some sources of fetal cells, eg cord blood, have been shown to be capable of crossing greater HLA mismatching resulting in less rejection and decreased immune mediated toxicities. Given the increasing focus on HES and advances in our basic knowledge of regenerative medicine it is an appropriate time to review the biology and use of fetal tissues. Human Fetal Tissue Transplantation is a timely publication that provides details of many aspects of the potential use of fetal tissues for therapeutic applications. As many tissues are wasted on a daily basis it appropriate to raise discussion on how to maximize access to discard tissue and at the same time engage in discussion of the ethics associated with fetal tissue procurement and clinical use. 606 $aHematology 606 $aPathology 606 $aHematology 606 $aPathology 615 0$aHematology. 615 0$aPathology. 615 14$aHematology. 615 24$aPathology. 676 $a617.95 701 $aBhattacharya$b Niranjan$01759407 701 $aStubblefield$b Phillip$01759408 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910438005303321 996 $aHuman fetal tissue transplantation$94197856 997 $aUNINA