LEADER 03363nam 2200565Ia 450 001 9910437991603321 005 20200520144314.0 010 $a3-642-36229-X 024 7 $a10.1007/978-3-642-36229-3 035 $a(CKB)2670000000406469 035 $a(EBL)1398731 035 $a(SSID)ssj0000962960 035 $a(PQKBManifestationID)11551243 035 $a(PQKBTitleCode)TC0000962960 035 $a(PQKBWorkID)10976286 035 $a(PQKB)10662308 035 $a(DE-He213)978-3-642-36229-3 035 $a(MiAaPQ)EBC1398731 035 $a(PPN)172425875 035 $a(EXLCZ)992670000000406469 100 $a20130729d2013 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aMyelodysplastic syndromes /$fJoachim Deeg ... [et. al.] 205 $a2nd ed. 2013. 210 $aNew York $cSpringer$d2013 215 $a1 online resource (245 p.) 225 0 $aHematologic malignancies 300 $aDescription based upon print version of record. 311 $a3-642-36228-1 320 $aIncludes bibliographical references and index. 327 $aClincial Presentation and Differential Diagnosis -- Epidemiology and Etiology -- Cytogenetic Diagnosis of Myelodysplastic Syndromes -- MDS Stem Cell  Biology -- The Biology of Myelodysplastic Syndrome Associated with Isolated del(5q) -- Other -- Overlap with MPN -- Classification and Staging of Myelodysplastic Syndromes -- Immunophenotyping in Myelodysplastic Syndrome -- Prognostic Models for Patients with Myelodysplastic Syndromes -- Low Risk MDS -- Management of High-Risk Myelodysplastic Syndrome -- Hematopoietic Cell Transplantation -- MDS in Children. 330 $aMyelodysplastic syndromes (MDS) have been studied intensively in recent years and knowledge of the disease process and underlying molecular defects in MDS has expanded rapidly.  With the aging of populations and the concurrent increase in the diagnosis of MDS, these findings are of central clinical importance. New prognostic classification systems with refined prognostic significance have been developed, and molecular abnormalities are now finding their way into the process of clinical decision-making. The book has been  completely updated since the first edition and concisely summarizes the state of the art on all aspects of MDS, including clinical presentation, etiology, epidemiology, molecular biology, classification, and staging. The different chapters provide  guidance on diagnosis and differential diagnosis, as well as on treatment strategies, including the use of hematopoietic growth factors, biology-based treatment, hematopoietic stem cell transplantation, and supportive care. MDS in children is also addressed in a separate chapter. This practically oriented book will be a valuable resource for a broad range of students and practitioners in the field.  . 410 0$aHematologic Malignancies,$x2197-9774 606 $aMyelodysplastic syndromes 606 $aHematological oncology 615 0$aMyelodysplastic syndromes. 615 0$aHematological oncology. 676 $a616 700 $aDeeg$b Joachim$01760618 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910437991603321 996 $aMyelodysplastic syndromes$94199666 997 $aUNINA