LEADER 05400nam 2200529Ia 450 001 9910437848303321 005 20200520144314.0 010 $a1-299-33562-4 010 $a1-4614-5930-3 024 7 $a10.1007/978-1-4614-5930-9 035 $a(OCoLC)828677066 035 $a(MiFhGG)GVRL6XIZ 035 $a(CKB)2670000000336363 035 $a(MiAaPQ)EBC1082038 035 $a(EXLCZ)992670000000336363 100 $a20130220d2013 uy 0 101 0 $aeng 135 $aurun|---uuuua 181 $ctxt 182 $cc 183 $acr 200 00$aCardiac remodeling $emolecular mechanisms /$fedited by Bodh I. Jugdutt, Naranjan S. Dhalla 205 $a1st ed. 2013. 210 $aNew York $cSpringer$d2013 215 $a1 online resource (xi, 569 pages) $cillustrations (some color) 225 1 $aAdvances in biochemistry in health and disease ;$v5 300 $aDescription based upon print version of record. 311 $a1-4899-9383-5 311 $a1-4614-5929-X 320 $aIncludes bibliographical references and index. 327 $aPart I: Molecular mechanisms of remodeling in pressure and volume overload hypertrophy and ehart failure -- ?-adrenergic receptor signaling pathway in heart failure -- Remodeling of potassium channels in cardiac hypertrophy -- Role of gender in Ca2+ cycling and cardiac remodeling due to heart failure -- The failing heart: is it an inefficient engine or an engine out of fuel? -- Regulation of cardiac hypertrophic remodeling by the USP15/SLIM1 pathway -- Role of galectin-3 pathways in the pathogenesis of cardiac remodeling and heart failure -- A mitochondriocentric pathway to cardiomyocyte necrosis:  an upstream molecular mechanism in myocardial fibrosis -- The ACE2/Ang (1-7) pathway in cardiac remodeling due to pressure-overload -- Local actions of natriuretic peptides and nitric oxide in cardiac remodelling: Implications for therapy -- Modulating G protein-coupled receptors to effect reverse cardiac remodeling -- Role of inflammation and matrix proteinases in cardiac remodeling following stress and injury -- Role of chymase in matrix and myocardial remodeling due to mitral regurgitation. Implications for therapy -- Cardiac remodeling due to aortic regurgitation and mitral regurgitation -- Reducing oxidative stress and manipulating molecular signaling events using resveratrol as a therapy for pathological cardiac hypertrophy -- Angiogenesis, arteriogenesis, and mitochondrial dysfunction -- Part II: Molecular mechanisms of remodeling after myocardial injury and infarction -- Subcellular remodeling and cardiac dysfunction due to ischemia-reperfusion injury -- Role of microRNAs in cardiac hypertrophy and post-infarction remodeling -- Negative regulators of inflammation as endogenous protective mechanisms in post-infarction remodeling -- TLR-dependent pathways and Akt/mTOR/P70S6K pathways in cardiac remodeling after myocardial infarction -- The STAT3 pathway and downstream mechanisms in cardiac remodeling: Friend or foe -- The role of growth differentiation factor 5 in cardiac repair post myocardial infarction -- Extracellular matrix biomarkers of adverse remodeling after myocardial infarction -- Oxidative stress in cardiac repair and remodeling: Molecular pathways and therapeutic strategies -- Role of SPARC in cardiac extracellular matrix remodeling after myocardial infarction -- Tissue inhibitor of matrix metalloproteinases in the pathogenesis of heart failure syndromes -- Intracellular matrix remodeling and cardiac function in ischemia-reperfusion injury -- Aging and markers of adverse remodeling after myocardial infarction -- Optimizing stem cell therapy for cardiac repair following a myocardial infarction -- Regulation of fibrosis after myocardial infarction. Implications for ventricular remodeling -- The ACE2/Ang-(1-7) pathway in cardiac fibroblasts as a potential target for cardiac remodeling. 330 $aThe main objective of Cardiac Remodeling: Molecular Mechanisms is to summarize the major research advances in molecular, biochemical and translational aspects of cardiac remodeling over the last 2 to 3 decades under one cover and touch on future directions. It provides a high profile and valuable publication resource on molecular mechanisms of cardiac remodeling for both the present and future generations of researchers, teachers, students and trainees. This book should stimulate future translational research targeted towards discovery and development for preventing, limiting and reversing bad remodeling over the next few decades, with the ultimate goal of preventing progression to systolic and/or diastolic heart failure. The chapters suggest potential novel strategies that should receive attention for translating basic research knowledge to application in patients at the bedside. 410 0$aAdvances in biochemistry in health and disease ;$v5. 606 $aVentricular remodeling$xMolecular aspects 606 $aVentricular remodeling$xTreatment 615 0$aVentricular remodeling$xMolecular aspects. 615 0$aVentricular remodeling$xTreatment. 676 $a616.12 701 $aJugdutt$b Bodh I$01752100 701 $aDhalla$b Naranjan S$01738794 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910437848303321 996 $aCardiac remodeling$94187313 997 $aUNINA LEADER 03620oam 2200733Ka 450 001 9910969362003321 005 20100917015550.0 010 $a9786612526244 010 $a9781282526242 010 $a1282526243 010 $a9781849507516 010 $a1849507511 035 $a(CKB)2670000000014624 035 $a(EBL)514072 035 $a(OCoLC)558634900 035 $a(SSID)ssj0000428616 035 $a(PQKBManifestationID)11305688 035 $a(PQKBTitleCode)TC0000428616 035 $a(PQKBWorkID)10424415 035 $a(PQKB)11417756 035 $a(MiAaPQ)EBC514072 035 $a(OCoLC)ocn558634900 035 $a(PPN)170272745 035 $a(Perlego)387896 035 $a(EXLCZ)992670000000014624 100 $a20100318d2010 uy 0 101 0 $aeng 135 $aurun||||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aInterdisciplinary legal studies $ethe next generation /$feditor, Austin Sarat 210 $aBingley , UK $cEmerald$d2010 215 $a1 online resource (268 p.) 225 1 $aStudies in law, politics and society,$x1059-4337;$vv. 51, special issue 300 $aDescription based upon print version of record. 311 08$a9781849507509 311 08$a1849507503 320 $aIncludes bibliographical references. 327 $a"Hybrid" justice at the Special Court for Sierra Leone / Sara Kendall -- Surviving property : resistance against urban housing nationalization during the transformation to communism (Romania, 1950-1965) / Mihaela Serban Rosen -- Disciplinary evolution of Turkish prisons, 1980s-1990s / Arda Ibikoglu -- "I'm Gonna Call My Lawyer" : shifting legal consciousness at the intersection of inequality / Diana Hernández -- A more global court? : a call for a new perspective on judicial globalization and its effect on the U.S. Supreme Court / Angela Narasimhan -- The sovereign city? : negotiating self-determination in an American military enclave / Erin E. Fitz-Henry -- Technique and technology in the kitchen : comparing resistance to municipal trans fat and foie gras bans / Michaela DeSoucey and David Schleifer -- Indigeneity : before and beyond the law / Kathleen Birrell. 330 $aThis volume of Studies in Law, Politics, and Society brings together research by graduate students from universities in the United States and the United Kingdom. The work of these students was singled out by their teachers and advisors as showing unusual promise and marking out directions for the next generationA" of interdisciplinary legal scholars. The research collected here is often comparative. It is theoretically informed and rigorous in its methods. Taken together it shows breadth and excellence, and it signals the continuing vibrancy of interdisciplinary legal studies. 410 0$aStudies in law, politics and society ;$vv. 51, special issue. 606 $aSociological jurisprudence 606 $aLaw and the social sciences 606 $aLaw & society$2bicssc 606 $aCourts & procedure$2bicssc 606 $aLaw$xGeneral$2bisacsh 606 $aLaw$xTrial Practice$2bisacsh 615 0$aSociological jurisprudence. 615 0$aLaw and the social sciences. 615 7$aLaw & society. 615 7$aCourts & procedure. 615 7$aLaw$xGeneral. 615 7$aLaw$xTrial Practice. 676 $a340.115 701 $aSarat$b Austin$0254475 801 0$bZJC 801 1$bZJC 801 2$bEBLCP 801 2$bZJC 906 $aBOOK 912 $a9910969362003321 996 $aInterdisciplinary legal studies$94462037 997 $aUNINA