LEADER 02678nam  2200589 a 450 
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010   $a1-283-93397-7
010   $a1-4614-5260-0
024 7 $a10.1007/978-1-4614-5260-7
035   $a(CKB)3400000000093740
035   $a(EBL)1081884
035   $a(OCoLC)821823520
035   $a(SSID)ssj0000810368
035   $a(PQKBManifestationID)11456329
035   $a(PQKBTitleCode)TC0000810368
035   $a(PQKBWorkID)10827033
035   $a(PQKB)11620405
035   $a(DE-He213)978-1-4614-5260-7
035   $a(MiAaPQ)EBC1081884
035   $a(PPN)168302527
035   $a(EXLCZ)993400000000093740
100   $a20121219d2013      uy         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 00$aAdvances in biology and therapy of multiple myeloma$hVolume 2$iTranslational and clinical research /$fNikhil C. Munshi, Kenneth C. Anderson, editors
205   $a1st ed. 2013.
210   $aNew York $cSpringer$d2013
215   $a1 online resource (290 p.)
300   $aDescription based upon print version of record.
311   $a1-4899-8914-5 
311   $a1-4614-5259-7 
320   $aIncludes bibliographical references and index.
327   $apt. I. Myeloma immune and antibody targets -- pt. II. New agents.
330   $aDespite the advances in conventional, and novel agent and high dose chemotherapy, multiple myeloma remains incurable. In order to overcome resistance to current therapies and improve patient outcome, novel biologically-based treatment approaches are being developed. Current translational research in multiple myeloma focusing on the development of molecularly-based novel targeted single-agent and combination therapies has great promise to achieve high frequency and durable responses in the majority of patients.   This volume will focus on biology of multiple myeloma, especially on oncogenomic changes, cell signaling pathways and intermediate molecules that are being investigated for development of novel therapies. The book will present newer developments, providing an emphasis on basic science, as well as its significant clinical impact.
606   $aMultiple myeloma
606   $aMedicine$xResearch
615  0$aMultiple myeloma.
615  0$aMedicine$xResearch.
676   $a616.99418
701   $aMunshi$b Nikhil C$01064467
701   $aAnderson$b Kenneth C$0876632
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910437847903321
996   $aAdvances in biology and therapy of multiple myeloma$92538380
997   $aUNINA