LEADER 02853nam 2200601Ia 450 001 9910437838703321 005 20200520144314.0 010 $a1-299-40798-6 010 $a94-007-5893-6 024 7 $a10.1007/978-94-007-5893-3 035 $a(CKB)2670000000328616 035 $a(EBL)1083674 035 $a(OCoLC)827212334 035 $a(SSID)ssj0000878732 035 $a(PQKBManifestationID)11486343 035 $a(PQKBTitleCode)TC0000878732 035 $a(PQKBWorkID)10837385 035 $a(PQKB)11788735 035 $a(DE-He213)978-94-007-5893-3 035 $a(MiAaPQ)EBC1083674 035 $a(PPN)168341980 035 $a(EXLCZ)992670000000328616 100 $a20130211d2013 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aDeveloping synthetic transport systems /$fAlexey Melkikh, Maria Sutormina 205 $a1st ed. 2013. 210 $aDordrecht $cSpringer$dc2013 215 $a1 online resource (203 p.) 225 0$aSpringerBriefs in biochemistry and molecular biology 300 $aDescription based upon print version of record. 311 $a94-007-5892-8 320 $aIncludes bibliographical references and index. 327 $aIntroduction. Biological Cybernetics and the optimization problem of transport of substances in the cells -- Models of ion transport in mammalian cells -- Models of ion transport and regulation in plant cells and unicellular organisms -- Optimization of the transport of substances in cells. Index. 330 $aUnderstanding the general laws of an effective system for the transport of substances in cells is an important goal of systems and synthetic biology and will help us to answer why the transport subsystem of a cell is arranged as it is. In addition, the construction of models for optimizing transport systems is of considerable importance in the early stages in the development of a functioning protocell. The aim of this book is to describe the latest techniques for the calculation of the optimal parameters of the transport subsystem of a cell at its maximum efficiency. The book will describe linear and nonlinear programming, dynamic programming, game theory for models of ion transport in different types of cells (e.g. mammalian cells, bacteria, plants and fungi). 410 0$aSpringerBriefs in Biochemistry and Molecular Biology 606 $aSystems biology 606 $aComputational biology 615 0$aSystems biology. 615 0$aComputational biology. 676 $a571.6/4 700 $aMelkikh$b Alexey$01064345 701 $aSutormina$b Maria$01761328 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910437838703321 996 $aDeveloping synthetic transport systems$94200685 997 $aUNINA