LEADER 02882nam 2200613 a 450 001 9910437828103321 005 20200520144314.0 010 $a1-283-93540-6 010 $a3-642-34617-0 024 7 $a10.1007/978-3-642-34617-0 035 $a(CKB)2670000000309174 035 $a(EBL)1082826 035 $a(OCoLC)823386668 035 $a(SSID)ssj0000810572 035 $a(PQKBManifestationID)11439148 035 $a(PQKBTitleCode)TC0000810572 035 $a(PQKBWorkID)10833168 035 $a(PQKB)10794493 035 $a(DE-He213)978-3-642-34617-0 035 $a(MiAaPQ)EBC1082826 035 $a(PPN)168327260 035 $a(EXLCZ)992670000000309174 100 $a20130111d2013 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aCalcium signalling $eapproaches and findings in the heart and blood /$fLars Kaestner 205 $a1st ed. 2013. 210 $aBerlin $cSpringer$d2013 215 $a1 online resource (246 p.) 300 $aDescription based upon print version of record. 311 $a3-642-34616-2 320 $aIncludes bibliographical references and index. 327 $aSummary -- Calcium Signalling Methodology -- Calcium Signalling in Cardiac Myocytes -- Calcium Signalling in Red Blood Cells -- Index. 330 $aThe book combines general concepts and methods to investigate calcium signalling in cells ranging from molecular biology approaches to manipulation of calcium in living cells. The focus within these methods in on the broad range of fluorescence imaging technology, in particular on optical sectioning techniques and fast image acquisition. In addition to these general guidelines there are application examples in a context beyond calcium signalling in two major fields: investigations of isolated cardiac myocytes and red blood cell related research. While the cellular cardiology section provides snapshots of certain calcium signalling aspects, the red blood cell part presents an overview from the functional identification of calcium-channels to a concept of physiological and pathophysiological relevance. 606 $aCalcium$xPhysiological effect$xResearch$xMethodology 606 $aCalcium$xAnalysis 606 $aSecond messengers (Biochemistry)$xResearch$xMethodology 606 $aCellular signal transduction$xResearch$xMethodology 615 0$aCalcium$xPhysiological effect$xResearch$xMethodology. 615 0$aCalcium$xAnalysis. 615 0$aSecond messengers (Biochemistry)$xResearch$xMethodology. 615 0$aCellular signal transduction$xResearch$xMethodology. 676 $a572.516 700 $aKaestner$b Lars$01060481 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910437828103321 996 $aCalcium signalling$92513700 997 $aUNINA