LEADER 03608nam 2200589 a 450 001 9910437825903321 005 20200520144314.0 010 $a1-283-69721-1 010 $a1-4614-5203-1 024 7 $a10.1007/978-1-4614-5203-4 035 $a(CKB)2670000000277802 035 $a(EBL)1030598 035 $a(OCoLC)819631467 035 $a(SSID)ssj0000790016 035 $a(PQKBManifestationID)11492150 035 $a(PQKBTitleCode)TC0000790016 035 $a(PQKBWorkID)10733483 035 $a(PQKB)10414581 035 $a(DE-He213)978-1-4614-5203-4 035 $a(MiAaPQ)EBC1030598 035 $a(PPN)168302330 035 $a(EXLCZ)992670000000277802 100 $a20120724d2013 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aCardiac adaptations $emolecular mechanisms /$fBohuslav Ostadal, Naranjan S. Dhalla, editors 205 $a1st ed. 2013. 210 $aNew York $cSpringer$d2013 215 $a1 online resource (466 p.) 225 0$aAdvances in biochemistry in health and disease ;$vv. 4 300 $aDescription based upon print version of record. 311 $a1-4939-0030-7 311 $a1-4614-5202-3 320 $aIncludes bibliographical references and index. 327 $apt. I. Developmental aspects of cardiac adaptation -- pt. II. Cardiac adaptations to overload -- pt. III. Molecular and cellular aspects of cardiac adaptations. 330 $aThe processes of adaptation and maladaptation play an important role in the pathogeny of serious cardiovascular diseases, such as hypertension, valvular diseases, congenital heart disease, myocardial infarction and different cardiomyopathies as well as during adaptation to exercise and high altitude hypoxia. This volume incorporates the rapidly developing basic and clinically relevant information on adaptive mechanisms, thereby contributing to the better understanding of possible prevention and therapy of life-threatening cardiovascular diseases.  The first section of this volume focuses on developmental aspects of cardiac adaptation, including chapters on comparative and molecular aspects of cardiac development, prenatal and postnatal developments, coronary vascular development, and ontogenetic adaptation to hypoxia, as well as cardiac and arterial adaptation during aging.  The second section is devoted to cardiac adaptations to overload on the heart, centered around the mechanisms of cardiac hypertrophy due to pressure overload, volume overload, exercise, gender difference, high altitude, and different pathological situations.  The third section of this volume highlights the roles of sympathetic nervous system with respect to ?-adrenoceptor and ?-adrenoceptor mechanisms in the development of cardiac hypertrophy.  Cardiac Adaptations will be of great value to cardiovascular investigators, who will find this book highly useful in their cardiovascular studies for finding solutions in diverse pathological conditions; it will also appeal to students, fellows, scientists, and clinicians interested in cardiovascular abnormalities. 410 0$aAdvances in Biochemistry in Health and Disease,$x2512-2150 ;$v4 606 $aCardiovascular system$xPhysiology 615 0$aCardiovascular system$xPhysiology. 676 $a616.1/05 701 $aOstadal$b Bohuslav$01757467 701 $aDhalla$b Naranjan S$01738794 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910437825903321 996 $aCardiac adaptations$94195322 997 $aUNINA