LEADER 03055nam 2200505Ia 450 001 9910437821703321 005 20241003094848.0 010 $a3-642-39109-5 024 7 $a10.1007/978-3-642-39109-5 035 $a(PPN)172427630 035 $a(OCoLC)857428001 035 $a(MiFhGG)GVRL6VDM 035 $a(CKB)3710000000015870 035 $a(MiAaPQ)EBC1398822 035 $a(EXLCZ)993710000000015870 100 $a20111102d2013 uy 0 101 0 $aeng 135 $aurun#---uuuua 181 $ctxt 182 $cc 183 $acr 200 00$aMolecular beacons /$fChaoyong James Yang, Weihong Tan, editors 205 $a1st ed. 2013. 210 $aBerlin ;$aHeidelberg $cSpringer-Verlag$d2013 215 $a1 online resource (ix, 194 pages) $cillustrations (some color) 225 0 $aGale eBooks 300 $aDescription based upon print version of record. 311 $a3-642-39108-7 320 $aIncludes bibliographical references. 327 $aDesign, Synthesis, Purification and Characterization of Molecular Beacons -- Thermodynamic and Kinetic Properties of Molecular Beacons -- Application of Molecular Beacons in Real-Time PCR -- Molecular Beacons for Detection of Single Nucleotide Polymorphisms -- Molecular Beacons on Solid Surfaces -- Functional materials for signal amplification of molecular beacons -- Engineering Molecular Beacons for Advanced Applications -- Excimer Molecular Beacon -- Strategies for Delivering Molecular Beacons into Cells -- Molecular Beacons for Intracellular Analysis: Challenges and Successes -- Molecular Aptamer Beacons. 330 $aMolecular Beacons explains working principle of molecular beacons, discusses their design, synthesis, purification and characterization, explores their thermodynamic and kinetic properties, and more importantly, reviews their in vivo and in vitro applications with the emphasis on the design and modification of molecular beacons for in vivo mRNA imaging applications. This book is designed to bring together in a single resource an organized and comprehensive view of molecular beacons and will be a valuable resource for academic, clinical and industrial scientists and graduate students who may consider exploring molecular beacons in their research or practice. Chaoyong James Yang is the Lu Jiaxi Professor of Chemistry at Xiamen University, China. Weihong Tan is a Distinguished Professor of Chemistry and Biomedical Engineering at Hunan University, China and also a University of Florida Distinguished Professor and V. T. and Louis Jackson Professor of Chemistry at the University of Florida, USA. 606 $aMolecular biology 606 $aCellular signal transduction 615 0$aMolecular biology. 615 0$aCellular signal transduction. 676 $a543 701 $aYang$b Chaoyong James$01762736 701 $aTan$b Weihong$01762737 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910437821703321 996 $aMolecular beacons$94202851 997 $aUNINA