LEADER 03936nam 2200625 a 450 001 9910437799503321 005 20200520144314.0 010 $a1-283-64063-5 010 $a3-642-32329-4 024 7 $a10.1007/978-3-642-32329-4 035 $a(CKB)3400000000086327 035 $a(EBL)1030347 035 $a(OCoLC)819505694 035 $a(SSID)ssj0000766990 035 $a(PQKBManifestationID)11419287 035 $a(PQKBTitleCode)TC0000766990 035 $a(PQKBWorkID)10739979 035 $a(PQKB)11073887 035 $a(DE-He213)978-3-642-32329-4 035 $a(MiAaPQ)EBC1030347 035 $a(PPN)168321572 035 $a(EXLCZ)993400000000086327 100 $a20120822d2013 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aDesigning receptors for the next generation of biosensors /$fvolume editors Sergey A. Piletsky, Michael J. Whitcombe ; with contributions by M.R. Andreu ... [et al.] 205 $a1st ed. 2013. 210 $aNew York $cSpringer$d2013 215 $a1 online resource (270 p.) 225 0$aSpringer series on chemical sensors and biosensors,$x1612-7617 ;$v12 300 $aDescription based upon print version of record. 311 $a3-642-42739-1 311 $a3-642-32328-6 320 $aIncludes bibliographical references and index. 327 $aMultichannel Sensors Based on Biphenyl and Cyclohexane Conformational Changes -- Learning from Proteins and Drugs: Receptors that Mimic Biomedically Important Binding Motifs -- Molecular Recognition of Nucleotides -- Molecular Recognition of Oligopeptides and Protein Surfaces -- Antimicrobial Peptides for Detection and Diagnostic Assays -- Plastic Antibodies -- Computational Approaches in the Design of Synthetic Receptors -- MIP Sensors on the Way to Real-World Applications -- Molecularly Imprinted Au Nanoparticle Composites for Selective Sensing Applications -- Design and Development of in vivo Sensor Systems: The Long and Tortured Road to a Self-Contained, Implantable Glucose Sensor for Diabetes Management -- Evolving Trends in Transition Metal-Modified Receptor Design and Function. 330 $aDespite achievements in the application of enzymes, antibodies and biological receptors to diagnostics and sensing, the last two decades have also witnessed the emergence of a number of alternative technologies based on synthetic chemistry. This volume shows how synthetic receptors can be designed with characteristics that make them attractive alternatives to biological molecules in the sensory and diagnostics fields, with contributions from leading experts in the area. Subjects covered include synthetic receptors for a range of biomolecules, the use of antimicrobial peptides for the detection of pathogenic microorganisms, the development of molecularly imprinted polymer (MIP) nanoparticles, the in silico design of MIPs and MIP-based sensors, and two chapters examining the development of sensors from an industrial point of view. The particular focus of all chapters is on practical aspects, either in the development process or the applications of the synthesized materials. This book will serve as an important reference work for business leaders and technology experts in the sensors and diagnostics sector. 410 0$aSpringer Series on Chemical Sensors and Biosensors, Methods and Applications,$x1612-7617 ;$v12 606 $aBiosensors$xDesign 606 $aCell receptors 615 0$aBiosensors$xDesign. 615 0$aCell receptors. 676 $a610/.28 701 $aPiletsky$b Sergey A$01755827 701 $aWhitcombe$b Michael J$01755828 701 $aAndreu$b M. R$01755829 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910437799503321 996 $aDesigning receptors for the next generation of biosensors$94192786 997 $aUNINA