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010   $a981-15-5807-8
024 7 $a10.1007/978-981-15-5807-8
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035   $a(DE-He213)978-981-15-5807-8
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100   $a20210123d2020      u|         0
101 0 $aeng
135   $aurnn|008mamaa
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aGlycosphingolipids Signaling /$fby Cheorl-Ho Kim
205   $a1st ed. 2020.
210  1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2020.
215   $a1 online resource (XVII, 181 p. 30 illus., 25 illus. in color.) 
311 08$a981-15-5806-X 
327   $a1. Glycosphingolipids (GSLs) -- 2. Mammal GSL synthesis via ER and Golgi network -- 3. The GSL dependent signaling -- 4. Viral protein interaction with host cells GSLs -- 5. Bacterial toxin protein interaction with host cells GSL -- 6. GSL signaling regulation.
330   $aThis book presents the latest knowledge and the most recent research results on glycosphingolipid (GSL)-mediated signaling. GSLs are important constituents of the plasma membrane that exert their distinct functions through binding to certain functional proteins. They play a role in various human diseases and also function as human alloantigens. Cellular GSLs are associated with many biological functions such as cellular oncotransformation, phenotype change, neuronal or embryonic development, regulation of cell division, cell?cell interaction, cell attachment, adhesion, and motility, and intracellular signaling via protein?carbohydrate or carbohydrate?carbohydrate interactions. This book opens by providing the key background on GSL glycan?receptor interactions and mammalian GSL synthesis. Up-to-date information is then presented on all aspects of GSL-dependent signaling. Viral protein and bacterial toxin protein interactions with host cell GSLs are examined in depth, and the concluding chapter is devoted to signaling regulation. The book should assist in the further development of new strategies against emerging infectious agents and intractable diseases.
606   $aMolecular genetics
606   $aCancer
606   $aGenetics
606   $aBiochemistry
606   $aBiological transport
606   $aCell membranes
606   $aMolecular Genetics
606   $aCancer Biology
606   $aGenetics and Genomics
606   $aBiochemistry
606   $aMembrane Trafficking
615  0$aMolecular genetics.
615  0$aCancer.
615  0$aGenetics.
615  0$aBiochemistry.
615  0$aBiological transport.
615  0$aCell membranes.
615 14$aMolecular Genetics.
615 24$aCancer Biology.
615 24$aGenetics and Genomics.
615 24$aBiochemistry.
615 24$aMembrane Trafficking.
676   $a571.74
700   $aKim$b Cheorl-Ho$01062709
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910437632003321
996   $aGlycosphingolipids signaling$92527907
997   $aUNINA