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010   $a981-15-6487-6
024 7 $a10.1007/978-981-15-6487-1
035   $a(CKB)5590000000433270
035   $a(DE-He213)978-981-15-6487-1
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035   $a(PPN)253251540
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100   $a20210627d2020      uy             0
101 0 $aeng
135   $aurnn|008mamaa
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 00$aImmunotherapy for Gastrointestinal Malignancies /$fedited by Ramakrishna Vadde; Ganji Purnachandra Nagaraju
205   $a1st ed. 2020.
210  1$aSingapore :$cSpringer,$d[2020]
210  4$d©2020
215   $a1 online resource (XII, 251 p. 34 illus., 27 illus. in color.) 
225 1 $aDiagnostics and Therapeutic Advances in GI Malignancies
311   $a981-15-6486-8 
327   $a1 Tumor heterogeneity: challenges and perspectives for gastrointestinal cancer therapy -- 2 immune composition of gastrointestinal tract of Gut -- 3 Immunomarkers for detection of GI malignancies -- 4 Immuno-therapeutics of gastrointestinal malignancies -- 5 Immune cell therapy against gastrointestinal tract cancers -- 6 Immune checkpoint inhibitors in gastrointestinal malignancies -- 7 Monoclonal Antibody therapy against gastrointestinal tract cancers -- 8 Therapeutic Vaccines for Gastrointestinal Malignancies -- 9 Immuno-Oncology of Oesophageal Cancer -- 10 Association between IL6 gene polymorphisms and gastric cancer risk: A meta-analysis of case-control studies -- 11 Immuno-oncology of colorectal cancer -- 12 Immune targets in colorectal cancer -- 13 Applications of computational biology in gastrointestinal malignancies. .
330   $aThis book reviews current immunotherapeutic strategies for gastrointestinal (GI) malignancies, including immune composition, immune checkpoint inhibitors, cell therapy, and peptide vaccines used to protect against esophageal, gastric, hepato-biliary, pancreatic and colorectal cancers. It also discusses the current challenges of using immunotherapy for the treatment of gastrointestinal malignancies. The book reviews highly sensitive and specific immunomarkers for the detection of GI malignancies, and examines therapeutic vaccines and the major cytokines involved in GI immunotherapy, as well as their basic biology and clinical applications. In closing, the book explores various aspects of computational biology for the detection and treatment of GI malignancies. .
410  0$aDiagnostics and therapeutic advances in GI malignancies.
606   $aBiomedicine, general
606   $aImmunology
606   $aCancer$xResearch
615  0$aBiomedicine, general.
615  0$aImmunology.
615  0$aCancer$xResearch.
676   $a660
702   $aNagaraju$b Ganji Purnachandra
702   $aVadde$b Ramakrishna
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bUtOrBLW
906   $aBOOK
912   $a9910437630803321
996   $aImmunotherapy for Gastrointestinal Malignancies$92519804
997   $aUNINA