LEADER 03548nam  22006735  450 
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010   $a1-4614-4660-0
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024 7 $a10.1007/978-1-4614-4660-6
035   $a(CKB)2670000000529989
035   $a(EBL)1081850
035   $a(OCoLC)826853733
035   $a(SSID)ssj0000878962
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035   $a(PQKBTitleCode)TC0000878962
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035   $a(DE-He213)978-1-4614-4660-6
035   $a(MiAaPQ)EBC1081850
035   $a(PPN)168300850
035   $a(EXLCZ)992670000000529989
100   $a20130109d2013      u|             0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aGenetic and Molecular Epidemiology of Multiple Myeloma$b[electronic resource] /$fedited by Suzanne Lentzsch
205   $a1st ed. 2013.
210  1$aNew York, NY :$cSpringer New York :$cImprint: Springer,$d2013.
215   $a1 online resource (130 p.)
300   $aDescription based upon print version of record.
311   $a1-4614-4659-7 
311   $a1-4899-9865-9 
320   $aIncludes bibliographical references and index.
327   $aPreface -- Genetics of Multiple Myeloma -- Gene expression signature in MGUS and multiple myeloma -- Cap-Dependent Protein Translation Initiation in Multiple Myeloma: an Attractive Target for Therapy -- IRES-dependent, CAP-independent translation in Multiple Myeloma -- Epigenetic gene silencing as a new target for multiple myeloma -- Role of Bone Disease in the Pathogenesis of Multiple Myeloma -- Index.
330   $aThis state-of-the-art book is written by a group of international experts to provide insight into the newest breakthroughs from basic pathogenesis to clinical aspects of multiple myeloma. The book provides a comprehensive overview of the genetic and molecular epidemiology of multiple myeloma in order to get a more refined and conclusive understanding of this disease.  Areas, which are covered include the characterization of different myeloma entities by genomics and proteomics, notch signaling and targeting protein translation as a new treatment for multiple myeloma, cell cycle control of plasma cell differentiation, the role of bone disease in the pathogenesis of multiple myeloma as well as the molecular interaction of multiple myeloma with a microenvironment. Genetic and Molecular Epidemiology of Multiple Myeloma is a valuable resource for cancer researchers, medical, surgical, and radiation oncologists.
606   $aCancer research
606   $aCell biology
606   $aHuman genetics
606   $aCancer Research$3https://scigraph.springernature.com/ontologies/product-market-codes/B11001
606   $aCell Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L16008
606   $aHuman Genetics$3https://scigraph.springernature.com/ontologies/product-market-codes/B12008
615  0$aCancer research.
615  0$aCell biology.
615  0$aHuman genetics.
615 14$aCancer Research.
615 24$aCell Biology.
615 24$aHuman Genetics.
676   $a571.6
676   $a599935
676   $a610
676   $a611.01816
702   $aLentzsch$b Suzanne$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910437621803321
996   $aGenetic and Molecular Epidemiology of Multiple Myeloma$92530768
997   $aUNINA