LEADER 02991nam 2200553Ia 450 001 9910437616503321 005 20200520144314.0 010 $a1-4614-7729-8 024 7 $a10.1007/978-1-4614-7729-7 035 $a(CKB)2670000000406487 035 $a(EBL)1398469 035 $a(SSID)ssj0000958031 035 $a(PQKBManifestationID)11530666 035 $a(PQKBTitleCode)TC0000958031 035 $a(PQKBWorkID)10985070 035 $a(PQKB)10412919 035 $a(DE-He213)978-1-4614-7729-7 035 $a(MiAaPQ)EBC1398469 035 $a(PPN)172419816 035 $a(EXLCZ)992670000000406487 100 $a20130731d2013 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aAdvances in HIV-1 assembly and release /$fEric O. Freed, editor 205 $a1st ed. 2013. 210 $aNew York $cSpringer$d2013 215 $a1 online resource (229 p.) 300 $aDescription based upon print version of record. 311 $a1-4899-9563-3 311 $a1-4614-7728-X 320 $aIncludes bibliographical references and index. 327 $aStructural Biology of HIV Assembly -- Cellular Trafficking Mechanisms in the Assembly and Release of HIV -- Packaging of the HIV-1 RNA Genome -- Synthesis of Functional and Variable HIV-1 Envelope Glycoproteins -- HIV-1 Budding -- HIV-1 Maturation -- Cell-to-Cell Transmission of HIV -- Virus Assembly as a Target for Antiretroviral Therapy. 330 $aOver the past decade, enormous progress has been made in understanding the late events in the HIV replication cycle.  This has been made possible by major advances in cell biology, virology, and structural biology.  The field continues to move forward rapidly, with important new discoveries being reported on a regular basis.  The impact of this progress across a broad spectrum of biomedical research has been substantial.  The increase in basic knowledge in the areas of HIV assembly, release, and maturation has been accompanied by new possibilities for therapeutic intervention.The work includes topics relating to basic molecular biology, cell biology, and structural biology of HIV assembly, coupled with more applied ideas of how this basic information can inform the field of antiretroviral research.  The book covers all major topics pertaining to the late stages of HIV replication, with leaders in each area recruited to contribute chapters in their areas of expertise . The topics will be sufficiently focused to allow authors the opportunity to cover the latest developments in detail. 606 $aHIV (Viruses) 606 $aMedical virology 615 0$aHIV (Viruses) 615 0$aMedical virology. 676 $a616.979201 701 $aFreed$b Eric O$01755404 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910437616503321 996 $aAdvances in HIV-1 assembly and release$94192176 997 $aUNINA