LEADER 04700nam 22007215 450 001 9910437612703321 005 20200630144512.0 010 $a1-4614-6176-6 010 $a1-283-94589-4 024 7 $a10.1007/978-1-4614-6176-0 035 $a(CKB)2670000000530128 035 $a(EBL)1082097 035 $a(OCoLC)823728891 035 $a(SSID)ssj0000870719 035 $a(PQKBManifestationID)11463458 035 $a(PQKBTitleCode)TC0000870719 035 $a(PQKBWorkID)10818545 035 $a(PQKB)11709830 035 $a(DE-He213)978-1-4614-6176-0 035 $a(MiAaPQ)EBC1082097 035 $a(PPN)168304848 035 $a(EXLCZ)992670000000530128 100 $a20130107d2013 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aImpact of Genetic Targets on Cancer Therapy /$fedited by Wafik S El-Deiry 205 $a1st ed. 2013. 210 1$aNew York, NY :$cSpringer New York :$cImprint: Springer,$d2013. 215 $a1 online resource (446 p.) 225 1 $aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v779 225 0$aAdvances in experimental medicine and biology,$x0065-2598 300 $aDescription based upon print version of record. 311 $a1-4614-6175-8 311 $a1-4899-9144-1 320 $aIncludes bibliographical references and index. 327 $aNovel antineoplastics targeting genetic changes in colorectal cancer -- Update on Clinical Trials: Genetic Targets in Breast Cancer -- Impact of Genetic Targets on Cancer Therapy in Esophagogastric Cancer -- Impact of Genetic Targets on Cancer Therapy: Liver Cancer -- Targeting the molecular phenotype of pancreatic cancer toward the goal of patient-tailored therapy -- Impact of genetic markers on treatment of Non-small cell lung cancer -- Impact of Genetic Targets on Therapy in Head and Neck Squamous Cell Carcinoma -- Tyrosine Kinase Targeted Treatment of Chronic Myelogenous Leukemia and Other Myeloproliferative Neoplasms -- Targeted Therapy of Multiple Myeloma -- Current and Future Trials of Targeted Therapies in Cutaneous Melanoma -- Current Approaches to Epigenetic therapy for the treatment of Mantle Cell Lymphoma -- Impact of Genetic Targets on Primary Brain Tumor Therapy: What?s Ready for Prime Time? -- Rational therapy for renal cell carcinoma based on its genetic targets -- Molecular and Genetic Markers of Follicular-Cell Thyroid Cancer: Etiology and Diagnostic and Therapeutic Opportunities -- Genetic Targets in Pediatric Acute Lymphoblastic Leukemia -- Emerging molecular therapies for the treatment of Acute Lymphoblastic Leukemia -- Impact of Genetic Targets on Prostate Cancer Therapy -- Small-Cell Lung Cancer: An Update on Targeted Therapies -- Impact of Genetic Targets on Cancer Therapy in Acute Myelogenous Leukemia -- Index. 330 $aThe volume provides a forum for original peer-reviewed short communications, full-length research and review articles on new research findings and developments on the topic of genetic targets on cancer therapies. As the field is highly important it requires co-operation between research communities from all over the world to share their knowledge and experience in order to move the field forward. Each chapter includes a discussion of the impact of the tumor microenvironment and cancer stem cells and cover current knowledge in this area as it pertains to the disease, including emerging therapy targeting the microenvironment and/or cancer stem cells. 410 0$aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v779 606 $aCancer research 606 $aHuman genetics 606 $aMedical microbiology 606 $aMedicine 606 $aCancer Research$3https://scigraph.springernature.com/ontologies/product-market-codes/B11001 606 $aHuman Genetics$3https://scigraph.springernature.com/ontologies/product-market-codes/B12008 606 $aMedical Microbiology$3https://scigraph.springernature.com/ontologies/product-market-codes/B16003 606 $aBiomedicine, general$3https://scigraph.springernature.com/ontologies/product-market-codes/B0000X 615 0$aCancer research. 615 0$aHuman genetics. 615 0$aMedical microbiology. 615 0$aMedicine. 615 14$aCancer Research. 615 24$aHuman Genetics. 615 24$aMedical Microbiology. 615 24$aBiomedicine, general. 676 $a616.994042 702 $aEl-Deiry$b Wafik S$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910437612703321 996 $aImpact of Genetic Targets on Cancer Therapy$92509568 997 $aUNINA