LEADER 04359nam 22006495 450 001 9910437612203321 005 20200701192559.0 010 $a1-283-62363-3 010 $a9786613936080 010 $a1-4614-4027-0 024 7 $a10.1007/978-1-4614-4027-7 035 $a(CKB)2670000000245722 035 $a(EBL)994594 035 $a(OCoLC)809068192 035 $a(SSID)ssj0000738343 035 $a(PQKBManifestationID)11435252 035 $a(PQKBTitleCode)TC0000738343 035 $a(PQKBWorkID)10790222 035 $a(PQKB)11537596 035 $a(DE-He213)978-1-4614-4027-7 035 $a(MiAaPQ)EBC994594 035 $a(PPN)168299070 035 $a(EXLCZ)992670000000245722 100 $a20120821d2013 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aMechanisms and Emerging Therapies in Tremor Disorders$b[electronic resource] /$fedited by Giuliana Grimaldi, Mario Manto 205 $a1st ed. 2013. 210 1$aNew York, NY :$cSpringer New York :$cImprint: Springer,$d2013. 215 $a1 online resource (489 p.) 225 1 $aContemporary Clinical Neuroscience,$x2627-535X 300 $aDescription based upon print version of record. 311 $a1-4899-9074-7 311 $a1-4614-4026-2 320 $aIncludes bibliographical references and index. 327 $aPart 1: Fundamental aspects -- Definition of tremor -- Membrane mechanisms of tremor -- Rodent models of tremor -- Advances in genetics of human tremor -- Musculo-skeletal models of tremor -- Part 2: The various forms of tremor in clinical practice: presentation and mechanism -- Physiological tremor -- Rest tremor -- Postural tremors -- Isometric tremor -- Essential Tremor and Other Forms of Kinetic Tremor -- Dystonic tremor -- Orthostatic tremor -- Vocal tremor -- Update in Familial Cortical Myoclonic tremor with Epilepsy (FCMTE) -- Post-traumatic tremor and Other Post-Traumatic Movement Disorders -- Psychogenic tremor -- Tremor in childhood -- Part 3: Assessment of tremor: clinical, neurophysiological and neuroimaging aspects -- Assessment of tremor: clinical and functional scales -- Instrumentation: classical and emerging techniques -- Signal processing -- Diffusion imaging in tremor -- The metabolic networks in Parkinson's disease -- Part 4: Therapies of tremor -- Pharmacological treatments of tremor -- Thalamotomy -- Brain Stimulation -- Dopaminergic Influences on Rest and Action Tremors and Emerging Therapies for Tremor. 330 $aTremor is intimately linked to the numerous interactions of the central and peripheral nervous system components tuning motor control, from the cerebral cortex up to the peripheral effectors. Activities of central generators, reflex loop delays, inertia, stiffness and damping are all factors influencing features of tremor. This book discusses the pathophysiology of tremor including membrane mechanisms and rodent models, the advances in genetics and the musculoskeletal models pertinent to body oscillations. The main forms of tremor encountered during clinical practice are considered, taking into account neuroimaging aspects. The book covers recent advances in methodologies and techniques of assessment, and provides practical informations for the daily management. In addition to pharmacological treatments, neurosurgical approaches such as deep brain stimulation (DBS) and thalamotomy are discussed. Emerging techniques under development are also introduced. Future challenges are also presented. 410 0$aContemporary Clinical Neuroscience,$x2627-535X 606 $aMedicine 606 $aNeurology  606 $aBiomedicine, general$3https://scigraph.springernature.com/ontologies/product-market-codes/B0000X 606 $aNeurology$3https://scigraph.springernature.com/ontologies/product-market-codes/H36001 615 0$aMedicine. 615 0$aNeurology . 615 14$aBiomedicine, general. 615 24$aNeurology. 676 $a616.74 676 $a617.4/8 702 $aGrimaldi$b Giuliana$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aManto$b Mario$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910437612203321 996 $aMechanisms and Emerging Therapies in Tremor Disorders$92537551 997 $aUNINA