LEADER 01986nam  2200361z- 450 
001 9910427731703321
005 20210211
010   $a82-15-04119-1
035   $a(CKB)4100000011665494
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/40384
035   $a(oapen)doab40384
035   $a(EXLCZ)994100000011665494
100   $a20202102d2020      |y         0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 00$aAdvancing Systems Epidemiology in Cancer - Exploring Trajectories of Gene Expression
210   $cScandinavian University Press (Universitetsforlaget)$d2020
215   $a1 online resource (187 p.)
311 08$a82-15-04120-5 
330   $aThis book introduces systems epidemiology, which is a new scientific discipline borne by novel technologies. These have opened up the potential for studies of temporal changes in the carcinogenic process and the response of the immune system, all measured as functional genomics: gene expression, microRNA and methylation. Systems epidemiology is an integrated approach based on epidemiological methods with biobanks designed for studies of the trajectories or curves of functional genomics moving from before diagnosis, at diagnosis and postdiagnostic. It demands new epidemiological designs, the globolomic one, new statistical methods for description and analyses of time changes and incorporating basic knowledge from reductionist experiments and clinical outcomes including molecular biomarkers of cancer tissue and normal tissues.
517   $aAdvancing Systems Epidemiology in Cancer
606   $aMedicine$2bicssc
610   $aCancer
610   $aepidemiology
615  7$aMedicine
700   $aEiliv Lund$4auth$01291000
906   $aBOOK
912   $a9910427731703321
996   $aAdvancing Systems Epidemiology in Cancer - Exploring Trajectories of Gene Expression$93021739
997   $aUNINA