LEADER 01911nam  2200325z- 450 
001 9910427731703321
005 20231214133246.0
010   $a82-15-04119-1
035   $a(CKB)4100000011665494
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/40384
035   $a(EXLCZ)994100000011665494
100   $a20202102d2020      |y             0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aAdvancing Systems Epidemiology in Cancer - Exploring Trajectories of Gene Expression
210   $cScandinavian University Press (Universitetsforlaget)$d2020
215   $a1 electronic resource (187 p.)
311   $a82-15-04120-5 
330   $aThis book introduces systems epidemiology, which is a new scientific discipline borne by novel technologies. These have opened up the potential for studies of temporal changes in the carcinogenic process and the response of the immune system, all measured as functional genomics: gene expression, microRNA and methylation. Systems epidemiology is an integrated approach based on epidemiological methods with biobanks designed for studies of the trajectories or curves of functional genomics moving from before diagnosis, at diagnosis and postdiagnostic. It demands new epidemiological designs, the globolomic one, new statistical methods for description and analyses of time changes and incorporating basic knowledge from reductionist experiments and clinical outcomes including molecular biomarkers of cancer tissue and normal tissues.
517   $aAdvancing Systems Epidemiology in Cancer
610   $aepidemiology
610   $aCancer
700   $aEiliv Lund$4auth$01291000
906   $aBOOK
912   $a9910427731703321
996   $aAdvancing Systems Epidemiology in Cancer - Exploring Trajectories of Gene Expression$93021739
997   $aUNINA