LEADER 03561nam 2200469 450 001 9910424639503321 005 20210324140210.0 010 $a981-15-5120-0 024 7 $a10.1007/978-981-15-5120-8 035 $a(CKB)4100000011513680 035 $a(DE-He213)978-981-15-5120-8 035 $a(MiAaPQ)EBC6380852 035 $a(PPN)260306118 035 $a(EXLCZ)994100000011513680 100 $a20210324d2020 uy 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aCancer stem cells $enew horizons in cancer therapies /$fSurajit Pathak, Antara Banerjee, editors 205 $a1st ed. 2020. 210 1$aSingapore :$cSpringer,$d[2020] 210 4$dİ2020 215 $a1 online resource (VII, 369 p. 65 illus., 58 illus. in color.) 311 $a981-15-5119-7 327 $aChapter 1. Introduction to cancer stem cells -- Chapter 2. Types of Cancer Stem Cells -- Chapter 3. Isolation and Characterization of Cancer Stem Cells (CSCs) -- Chapter 4. Lung and Prostate Cancer Stem Cells -- Chapter 5. A differential role of miRNAs in regulation of breast cancer stem cells -- Chapter 6. Skin stem cells in cancer -- Chapter 7. Ocular Cancer stem cells: Advances in therapeutic interventions -- Chapter 8. Cancer Stem Cells and Tumour Aggressiveness -- Chapter 9. Therapeutic Implication of Cancer Stem Cells.-Chapter 10. Glioblastoma stem cells as a therapeutic target -- Chapter 11. Cancer stem cells and therapeutic angiogenesis -- Chapter 12. Cancer stem cells as a seed for cancer metastasis -- Chapter 13. Functionality of intron specific genes and cancer stem cells in the progression of colorectal cancer -- Chapter 14. Technological advancement in Cancer Stem Cell Research -- Chapter 15. Controversies in Isolation and Characterization of Cancer Stem Cells -- Chapter 16. Targeting therapies for cancer stem cells -- Chapter 17. Targeting Cancer stem cells by nanoenabled drug delivery -- Chapter 18. Cancer Stem Cells in Patients Survival and Therapies in Cancer.-. 330 $aThis book discusses the recent developments in the therapeutic implications of cancer stem cells for the effective diagnosis, prognosis, and treatment of cancer. It summarizes the various stem cells of common cancers including colon, pancreas, lungs, prostate, melanoma, and glioblastoma, and reviews the potential role of cancer stem cells in tissue aggressiveness, examining the functional contribution of cancer stem cells in the establishment and recurrence of cancerous tumors. Further, it explores the potential of cancer stem cells as novel therapeutic targets for the treatment and prevention of tumor progression. The book also discusses the various approaches for detecting, isolating, and characterizing different cancer stem cells and signaling pathways that control their replication, survival, and differentiation. Lastly, it explores the key features and mechanisms of drug resistance, chemo-resistance, and radio-resistance in cancer stem cells to improve therapeutic rationale. 606 $aCancer$xResearch 606 $aCancer$xTreatment$xTechnological innovations 615 0$aCancer$xResearch. 615 0$aCancer$xTreatment$xTechnological innovations. 676 $a616.9940072 702 $aPathak$b Surajit 702 $aBanerjee$b Antara 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910424639503321 996 $aCancer stem cells$91123439 997 $aUNINA