LEADER 03443nam 22005775 450 001 9910416133903321 005 20250609112032.0 010 $a3-030-51878-7 024 7 $a10.1007/978-3-030-51878-3 035 $a(CKB)4100000011384240 035 $a(DE-He213)978-3-030-51878-3 035 $a(MiAaPQ)EBC6307185 035 $a(PPN)269146903 035 $a(MiAaPQ)EBC6301504 035 $a(EXLCZ)994100000011384240 100 $a20200813d2020 u| 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aDiagnosis and Management of Myelodysplastic Syndromes $eA Clinical Guide /$fedited by Aziz Nazha 205 $a1st ed. 2020. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2020. 215 $a1 online resource (XII, 179 p. 29 illus., 28 illus. in color.) 300 $aIncludes index. 311 08$a3-030-51877-9 327 $aEpidemiology, Etiology, and Clinical Presentation of Myelodyplastic Syndromes -- Morphological, Flow Cytometry, and Cytogenetic Diagnosis of MDS -- Biology and Pathophysiology of MDS with del5q -- MDS Stem Cell Biology -- Molecular Landscape of MDS -- MDS Mimics (CHIP, ICUS, CCUS) -- Prognostic Models in Myelodyplastic Syndromes -- Treatment Algorithms for Lower-risk Disease -- Treatment Algorithms for Higher-risk Disease -- Hematopoietic Cell Transplantation for MDS Patients. 330 $aMyelodysplastic syndromes (MDS) are a group of clonal disorders characterized by pancytopenias and the risk of progression to acute myeloid leukemia. The diagnosis of MDS can be challenging, while the outcomes of MDS patients vary widely. This book provides a concise yet comprehensive overview of MDS. The book begins by reviewing the diagnostic workup of MDS, with a specific focus on the 2016 WHO criteria for MDS diagnosis, and the biology and pathophysiology of the disease. The text then presents the molecular landscape of MDS and its impact on disease diagnosis, prognosis, and treatment decisions. The book continues by profiling different prognostic models of MDS and concludes with a thorough review of treatment algorithms for lower and higher-risk MDS, as well as the use of hematopoietic stem cell transplant to combat the disease. Written by experts in the field, Diagnosis and Management of Myelodysplastic Syndromes: A Clinical Guide is a valuable resource for clinicians, practitioners, and researchers who are interested in MDS. The text also features over 100 illustrations, photographs, and tables. . 606 $aHematology 606 $aOncology 606 $aHematology$3https://scigraph.springernature.com/ontologies/product-market-codes/H3307X 606 $aOncology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33160 606 $aLeucèmia mieloide$2thub 606 $aOncologia$2thub 608 $aLlibres electrònics$2thub 615 0$aHematology. 615 0$aOncology. 615 14$aHematology. 615 24$aOncology. 615 7$aLeucèmia mieloide 615 7$aOncologia 676 $a616.41 702 $aNazha$b Aziz$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910416133903321 996 $aDiagnosis and Management of Myelodysplastic Syndromes$91990839 997 $aUNINA