LEADER 03668nam 22005775 450 001 9910416109103321 005 20251113211915.0 010 $a981-15-3797-6 024 7 $a10.1007/978-981-15-3797-4 035 $a(CKB)4100000011343352 035 $a(DE-He213)978-981-15-3797-4 035 $a(MiAaPQ)EBC6272257 035 $a(PPN)260303062 035 $a(MiAaPQ)EBC6263997 035 $a(EXLCZ)994100000011343352 100 $a20200709d2020 u| 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aEarly-life Environmental Exposure and Disease $eFacts and Perspectives /$fedited by Yankai Xia 205 $a1st ed. 2020. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2020. 215 $a1 online resource (XVI, 239 p. 22 illus., 17 illus. in color.) 311 08$a981-15-3796-8 320 $aIncludes bibliographical references. 327 $aPreface -- Environmental Exposure Measurements and Evaluations -- Prenatal Smoke Exposure and Child Health -- Prenatal Pesticide Exposure and Child Health -- Prenatal Metal Exposure and Child Health -- Prenatal Stress and Child Health -- The Special Vulnerabilities of Child to Environmental Hazards -- Early-life Environmental Influences on Growth -- Early-life Environmental Influences on Neural Development -- Early-life Environmental Influences on Allergic Diseases -- Early-life Social and Economic Adversities on Health -- Endocrine Disrupting Chemical Exposure and Later-onset Diseases -- Paternal Specific Exposure and Child Health -- Molecular Mechanism of Early-life Chemical Exposure Induced Harmful Effects -- Transgenerational Effects on Developmental Origins of Diseases. 330 $aThis book offers valuable insights into the latest concepts and findings from epidemiologic, clinical and basic studies in the burgeoning area of early-life environmental exposure and diseases. The book is divided into five parts, starting with an overview of environmental exposure measurement and evaluation, followed by a review of the effects of exposure to various substances like tobacco smoke, pesticides and metals as well as stress on offspring?s health. It then discusses the developmental origins of a range of childhood diseases that affect growth, neural development and the immune system, and highlights the importance of longitudinal studies that measure exposure at potentially sensitive time points during childhood. It also provides up-to-date evidence of the intergenerational/transgenerational effects of early-life environmental exposure, especially via genetic and epigenetic pathways. Allowing readers to gain a thorough understanding of the predominating aspects of early-life environmental exposure and diseases, the book also provides a basis for developing environmental and health policies that could have wide and long-term impacts on human health. . 606 $aPharmacology 606 $aGynecology 606 $aEnvironmental health 606 $aPharmacology 606 $aGynecology 606 $aEnvironmental Health 615 0$aPharmacology. 615 0$aGynecology. 615 0$aEnvironmental health. 615 14$aPharmacology. 615 24$aGynecology. 615 24$aEnvironmental Health. 676 $a615 702 $aXia$b Yankai$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910416109103321 996 $aEarly-life Environmental Exposure and Disease$92546181 997 $aUNINA 999 $a08