LEADER 00988nam a2200265 i 4500 001 991002988719707536 005 20021022144600.0 008 960610s1952 it ||| | ita 035 $ab11738479-39ule_inst 035 $aLE021FD224070$9ExL 040 $aDip. SSSC$bita 100 1 $aDe Bartholomaeis, Vincenzo$0189438 245 10$aOrigini della poesia drammatica italiana /$cVincenzo De Bartholomaeis 250 $a2. ed. accresciuta e illustrata 260 $aTorino :$bSEI,$c1952 300 $aXVI, 522 p. :$bill. ;$c25 cm. 650 4$aDramma sacro 650 4$aLetteratura drammatica$zItalia 650 4$aStoria della letteratura 907 $a.b11738479$b21-09-06$c24-10-02 912 $a991002988719707536 945 $aLE021FD TI19C4$g1$iLE021FD-2366$lle023$nFondo D'Amico$o-$pE0.00$q-$rn$so $t0$u0$v0$w0$x0$y.i11978375$z24-10-02 996 $aOrigini della poesia drammatica italiana$9561004 997 $aUNISALENTO 998 $ale021$b10-06-96$cm$da $e-$fita$git $h0$i1 LEADER 01995nas 2200445 n 450 001 990008896860403321 005 20240229084548.0 011 $a1029-564X 035 $a000889686 035 $aFED01000889686 035 $a(Aleph)000889686FED01 035 $a000889686 091 $2CNR$aP 00005547 100 $a20161109b19391953km-y0itaa50------ba 101 0 $aita 102 $aLB 110 $aauu-------- 200 1 $aAnnali del Museo Libico di Storia Naturale 207 1$a1939-1953 210 $aTripoli$cGoverno della Libia 326 $aAnnuale 530 0 $aAnnali del Museo Libico di Storia Naturale 675 $a55 675 $a56 675 $a58 675 $a59 712 02$aMuseo Libico di Storia Naturale 801 0$aIT$bACNP$c20090723 859 4 $uhttp://acnp.cib.unibo.it/cgi-ser/start/it/cnr/dc-p1.tcl?catno=2694&person=false&language=ITALIANO&libr=&libr_th=unina1$zBiblioteche che possiedono il periodico 901 $aSE 912 $a990008896860403321 958 $aBiblioteca del Gruppo Geomineralogico - Università degli studi di Napoli Federico II$b1939-1953.$eSc. 15$fGM1 958 $aBiblioteca del Dipartimento di Entomologia e Zoologia Agraria dell'Università degli Studi di Napoli Federico II$b1939-1940;$fDAGEN 959 $aGM1 959 $aDAGEN 996 $aAnnali del Museo Libico di Storia Naturale$9801257 997 $aUNINA AP1 8 $6866-01$aNA081 Biblioteca del Gruppo Geomineralogico - Università degli studi di Napoli Federico II$bSc. 15$elargo San Marcellino, 10, 80138 Napoli (NA)$m0812538157$nit AP1 8 $6866-02$aNA219 Biblioteca del Dipartimento di Entomologia e Zoologia Agraria dell'Università degli Studi di Napoli Federico II$eVia Università, 100, 80055 Portici (NA)$m0812539188$m0817755145$nit AP2 40$aacnp.cib.unibo.it$nACNP Italian Union Catalogue of Serials$uhttp://acnp.cib.unibo.it/cgi-ser/start/it/cnr/df-p.tcl?catno=2694&language=ITALIANO&libr=&person=&B=1&libr_th=unina&proposto=NO LEADER 04628nam 22006735 450 001 9910416108503321 005 20251113204345.0 010 $a981-15-5652-0 024 7 $a10.1007/978-981-15-5652-4 035 $a(CKB)4100000011343398 035 $a(DE-He213)978-981-15-5652-4 035 $a(MiAaPQ)EBC6272252 035 $a(PPN)260303623 035 $a(MiAaPQ)EBC6264051 035 $a(EXLCZ)994100000011343398 100 $a20200710d2020 u| 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aGM3 Signaling /$fby Cheorl-Ho Kim 205 $a1st ed. 2020. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2020. 215 $a1 online resource (VII, 138 p. 32 illus., 26 illus. in color.) 311 08$a981-15-5651-2 327 $a1. History of sialic acids, gangliosides and GM3 -- 2. Synthesis of GM3 -- 3. Molecular localization of GM3 in cells -- 4. Basic function of GM3 as an interacting molecule -- 5. GD3 mimetics with a neurite forming capacity -- 6. GM3 as a pathogenic infection receptor -- 7. GM3 and related gangliosides prevent inflammation and atherosclerosis -- 8. GM3 has an anti-tumor capacity -- 9. GM3 suppresses tumor angiogenesis -- 10. Interaction between EGFR and GM3 -- 11. Membrane ganglioside-specific neuraminidase 3 (NEU3) regulates GM3 signaling -- 12. Regulation of GM3-mediated EGFR signaling by NEU3 sialidase -- 13. VEGFR-GM3 interaction in angiogenesis -- 14. GM3, competing with GM1, interaction with urokinase plasminogen activator receptor (uPAR) in endothelial caveolar-lipid rafts inhibits angiogenesis -- 15. GM3 interacts with TGF? Rs in the epithelial-mesenchymal transition (EMT) during posterior capsular opacification (PCO) formation -- 16. Galectin-1 promotes tumor growth and escapes immune surveillance -- 17. GM3-HGFR, FGFR and PDGFR cancer cell behavior, and IGF-1R in diabetic wound healing -- 18. GM3, caveolin-1 and insulin receptor in insulin resistance -- 19. GM3 suppresses arthritis -- 20. GM3 protects cochlear hair cells and hearing from corti degeneration -- 21. GM3 increases osteoclast differentiation via direct GM3 cooperation with RANKL and IGF-1 -- 22. GM3 in leukemic cells into terminal differentiation -- 23. ?2,3-Sialyllactose (3SL) or ?2,6-sialyllactose (6SL) of GM3 glycan in innate immunity. . 330 $aThis book reviews recent progress in understanding of the signaling and biochemistry of GM3 ganglioside in eukaryotic cells. GM3 is the simplest of the gangliosides and the precursor of other gangliosides. It is expressed in the outer leaflet of plasma cell membranes and has roles in the recognition, interaction, binding, adhesion, and motility of cells. In addition, GM3 has been documented to have functional roles in cell migration, proliferation, senescence, and apoptosis. The full range of topics of interest are addressed in the book. The early chapters discuss the synthesis of GM3, its molecular localization in cells, and its basic function as an interacting molecule. The ways in which GM3 exerts its effects via various growth factor receptors are fully explored. Current knowledge of the part played by GM3 in health and disease is discussed in depth. For example, its roles in preventing inflammation, inhibiting tumor angiogenesis and tumor growth, and suppressing arthritis are highlighted, and attention drawn to the significance of GM3 as a driver of impaired wound healing in diabetics. The book will be of interest to all who want a comprehensive update on research in this field. 606 $aMolecular genetics 606 $aCancer 606 $aGenetics 606 $aBiochemistry 606 $aBiological transport 606 $aCell membranes 606 $aMolecular Genetics 606 $aCancer Biology 606 $aGenetics and Genomics 606 $aBiochemistry 606 $aMembrane Trafficking 615 0$aMolecular genetics. 615 0$aCancer. 615 0$aGenetics. 615 0$aBiochemistry. 615 0$aBiological transport. 615 0$aCell membranes. 615 14$aMolecular Genetics. 615 24$aCancer Biology. 615 24$aGenetics and Genomics. 615 24$aBiochemistry. 615 24$aMembrane Trafficking. 676 $a378.1662 700 $aKim$b Cheorl-Ho$4aut$4http://id.loc.gov/vocabulary/relators/aut$01062709 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910416108503321 996 $aGM3 Signaling$92546180 997 $aUNINA