LEADER 04276nam 22006135 450 001 9910416107603321 005 20240208151204.0 010 $a3-030-50494-8 024 7 $a10.1007/978-3-030-50494-6 035 $a(CKB)4100000011343519 035 $a(DE-He213)978-3-030-50494-6 035 $a(MiAaPQ)EBC6273321 035 $a(PPN)258059605 035 $a(EXLCZ)994100000011343519 100 $a20200715d2020 u| 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aPediatric Pharmacotherapy /$fedited by Wieland Kiess, Matthias Schwab, Johannes van den Anker 205 $a1st ed. 2020. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2020. 215 $a1 online resource (VIII, 538 p. 1 illus.) 225 1 $aHandbook of Experimental Pharmacology,$x1865-0325 ;$v261 311 $a3-030-50493-X 320 $aIncludes bibliographical references. 327 $aAnti-epileptic drugs in pediatrics -- Current and new therapies for Duchenne Muscular Dystrophy -- Lysosomal diseases -- Mitochondriopathies -- Endocrinology thyroid, pituitary, growth stimulant, growth reduction -- Bone disease ? bisphosphonates -- Diabetes type 1 and 3 (insulin; sulfonylurea; others) -- Diabetes type 2 (metformin etc.) -- Dermatology ? part 1 urticaria, atopic dermatitis -- Dermatology part 2, ichtyosis, psoriasis -- Cardiovascular part 1- catcholamines, inotropic -- Cardiovascular part 2 ? antiarhythmica, anti hypertensives -- Nephrology ? dialysis -- How to use drugs in obese children and adolescents -- Haematology ? CSFs, erythropoietin -- Antiretroviral/HIV -- Clinical pharmacology and pharmacometrics to better understand physiological changes during pregnancy and neonatal life -- Antihelminth treatment -- Inflammatory bowel disease -- Constipation; laxatives -- Psychiatric diseases in children and adolescents -- Oncology ? cell reducing agents part 1, part 2, part 3 -- Immunosuppressants ? organ transplantation -- Bone marrow/stem cell transplantation -- Narcotic sparing approaches and the shift towards paracetamol in neonatal intensive care -- Disorders of puberty: pharmacotherapeutic strategies for management. 330 $aThis volume provides readers with the most updated scientific information on the efficacy and safety of medicines for children and adolescents. The book enriches the understanding of pediatric pharmacotherapy for health professionals, regulatory agencies, pharmaceutical companies and learned societies. It contains important information on the pharmacodynamics and pharmacokinetics of drugs. It summarizes the latest investigations on the effects of pharmacological treatments in relation to and dependent on age, gender, fat mass and disease status. Therefore and importantly, this volume reviews the latest data on how pharmacotherapy has to be adjusted and personalized in regards to stages of development and during the pediatric lifespan from neonate through adolescence. In addition, the topic of rare diseases and special challenges for pharmacotherapy will be included and will provide readers with the necessary knowledge to handle complex diseases and treatment strategies especially in relation to pharmacotherapy of rare and orphan diseases. 410 0$aHandbook of Experimental Pharmacology,$x1865-0325 ;$v261 606 $aPharmacology 606 $aPediatrics 606 $aPharmacology 606 $aPediatrics 606 $aQuimioteràpia$2thub 606 $aPediatria$2thub 608 $aLlibres electrònics$2thub 615 0$aPharmacology. 615 0$aPediatrics. 615 14$aPharmacology. 615 24$aPediatrics. 615 7$aQuimioteràpia 615 7$aPediatria 676 $a615.1083 702 $aKiess$b Wieland$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aSchwab$b Matthias$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $avan den Anker$b Johannes$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910416107603321 996 $aPediatric pharmacotherapy$91765297 997 $aUNINA