LEADER 03458nam 22006015 450 001 9910416106703321 005 20251113183640.0 010 $a981-15-3658-9 024 7 $a10.1007/978-981-15-3658-8 035 $a(CKB)4100000011354667 035 $a(DE-He213)978-981-15-3658-8 035 $a(MiAaPQ)EBC6272294 035 $a(PPN)260304840 035 $a(MiAaPQ)EBC6270849 035 $a(EXLCZ)994100000011354667 100 $a20200720d2020 u| 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAntimicrobial Resistance $eGlobal Challenges and Future Interventions /$fedited by Sabu Thomas 205 $a1st ed. 2020. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2020. 215 $a1 online resource (XIII, 230 p. 20 illus., 16 illus. in color.) 311 08$a981-15-3657-0 327 $a1) The Evolution of Microbial Defense Systems against Antimicrobial Agents -- 2) Carbapenem Resistance in Gram-negative bacilli: Mechanisms and Challenges -- 3) Influence of Antimicrobials on the Gut Microbiota -- 4) Influence of Abiotic Factors in the Emergence of Antibiotic Resistance -- 5) Polluted Coastal and Estuarine Environments ? A Potential Reservoir for AMR Determinants in Various Pathogenic Bacteria -- 6) AMR in Animal Health: Issues and One Health Solutions for LMICs -- 7) Antifungal Resistance: Current Concepts -- 8) 'Planetary Health? Perspectives and Alternative Approaches to Tackle the AMR Challenge -- 9) Use of Bacterial Cell Wall Recycle Inhibitors to Combat AMR in Bacteria -- 10) Status quo of Omics Technologies in Analyzing the Genetic Mediators of Antimicrobial Resistance at Sub-MIC Concentrations. 330 $aAntimicrobial resistance is a major global public health problem. This book focuses on the clinical implications of multi-drug resistant pathogens; tracking AMR and its evolutionary significance; antifungal resistance; and current and alternative treatment strategies for AMR, including antivirulent, antibiofilm and antimicrobial resistance breakers, repurposing of drugs, and probiotic therapy. Advances in antimicrobial stewardship, antibiotic policies from a global perspective and their impacts are also discussed. The book also explores the use of omics approaches to gain insights into antibacterial resistance, and includes chapters on the potential benefits of a ?One Health approach? describing the environmental and zoonotic sources of resistant genes and their effects on the global resistance pool. . 606 $aPharmaceutical chemistry 606 $aPharmacology 606 $aMedical microbiology 606 $aIndustrial microbiology 606 $aPharmaceutics 606 $aPharmacology 606 $aMedical Microbiology 606 $aIndustrial Microbiology 615 0$aPharmaceutical chemistry. 615 0$aPharmacology. 615 0$aMedical microbiology. 615 0$aIndustrial microbiology. 615 14$aPharmaceutics. 615 24$aPharmacology. 615 24$aMedical Microbiology. 615 24$aIndustrial Microbiology. 676 $a615 702 $aThomas$b Sabu$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910416106703321 996 $aAntimicrobial Resistance$91935231 997 $aUNINA