LEADER 04680nam 22006975 450 001 9910416105103321 005 20220615163825.0 010 $a981-15-5999-6 024 7 $a10.1007/978-981-15-5999-0 035 $a(CKB)4100000011354839 035 $a(DE-He213)978-981-15-5999-0 035 $a(MiAaPQ)EBC6272229 035 $a(PPN)260304913 035 $a(EXLCZ)994100000011354839 100 $a20200720d2020 u| 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aPharmacotherapeutic Botanicals for Cancer Chemoprevention /$fedited by Manish Kumar, Ashita Sharma, Praveen Kumar 205 $a1st ed. 2020. 210 1$aSingapore :$cSpringer Singapore :$cImprint: Springer,$d2020. 215 $a1 online resource (XII, 337 p. 120 illus., 39 illus. in color.) 311 $a981-15-5998-8 327 $aChapter 1. Phytochemicals in Cancer Chemoprevention: A Brief Perspective -- Chapter 2. Phytochemicals in Modulating Signalling Cascades in Cancer Cells -- Chapter 3. Diverse cancer therapeutic interactions: complexities in cancer management -- Chapter 4. Natural Products as Chemosensitizers for Adjunct Therapy in Cancer Management -- Chapter 5. Dietary phytochemicals as epigenetic modulators in cancer prevention: Emerging research trends, gaps, and future perspectives -- Chapter 6. Modulation of Cancer Cell Metabolism and Microenvironment by Phytochemicals -- Chapter 7. Role of Nutrigenetics and Nutrigenomics in Cancer Chemoprevention -- Chapter 8. Nano-delivery carriers for Enhanced Bioavailability of Antitumor Phytochemicals -- Chapter 9. Biphasic Effects of Phytochemicals and their Relevance to Cancer Therapeutics -- Chapter 10. Potential Pharmacotherapeutic Phytochemicals from Zingiberaceae for Cancer Prevention -- Chapter 11. 3 Dimensional Cell Culture Techniques in Cancer Research -- Chapter 12. Animal Models Systems of Cancer for Preclinical Trials -- Chapter 13. Cancer Chemoprevention by Natural Plant Products and Their Derivatives: Clinical Trials. 330 $aThe book presents a comprehensive and up-to-date overview of phytochemicals as efficient cancer therapeutics. Over the last few decades there has been a paradigm shift from conventional cancer therapeutic approaches to alternative and complementary medicinal approaches especially using phytoconstituents from natural products. As such, the book provides an in-depth understanding of phytochemicals targeting diverse signaling pathways involved in cancer along with the evaluation of the cancer modulatory effects of phytochemicals. It also highlights the potential modulatory effect of single nucleotide polymorphisms (SNPs) on the cancer-associated cellular pathways and their interactions with the phytochemicals. Further, it analyzes the drug delivery methods, bioavailability of active components of botanicals, and toxicity of phytochemicals. Lastly, the book elucidates the 3D cell culture and animal models systems to analyze the beneficial effects of phytochemicals in cancer. 606 $aCancer research 606 $aHuman genetics 606 $aPharmaceutical technology 606 $aBioinformatics 606 $aCancer Research$3https://scigraph.springernature.com/ontologies/product-market-codes/B11001 606 $aHuman Genetics$3https://scigraph.springernature.com/ontologies/product-market-codes/B12008 606 $aPharmaceutical Sciences/Technology$3https://scigraph.springernature.com/ontologies/product-market-codes/B21010 606 $aBioinformatics$3https://scigraph.springernature.com/ontologies/product-market-codes/L15001 606 $aFitoquímica$2thub 606 $aMedicina preventiva$2thub 606 $aCàncer$2thub 608 $aLlibres electrònics$2thub 615 0$aCancer research. 615 0$aHuman genetics. 615 0$aPharmaceutical technology. 615 0$aBioinformatics. 615 14$aCancer Research. 615 24$aHuman Genetics. 615 24$aPharmaceutical Sciences/Technology. 615 24$aBioinformatics. 615 7$aFitoquímica 615 7$aMedicina preventiva 615 7$aCàncer 676 $a361.32 702 $aKumar$b Manish$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aSharma$b Ashita$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aKumar$b Praveen$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910416105103321 996 $aPharmacotherapeutic Botanicals for Cancer Chemoprevention$92509548 997 $aUNINA