LEADER 03793nam 22006375 450 001 9910416101103321 005 20220328134553.0 010 $a3-030-49406-3 024 7 $a10.1007/978-3-030-49406-3 035 $a(CKB)4100000011384220 035 $a(DE-He213)978-3-030-49406-3 035 $a(MiAaPQ)EBC6301683 035 $a(PPN)250216930 035 $a(EXLCZ)994100000011384220 100 $a20200810d2020 u| 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aCavernomas of the CNS $eBasic Science to Clinical Practice /$fedited by Ond?ej Bradá?, Vladimír Bene? 205 $a1st ed. 2020. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2020. 215 $a1 online resource (VIII, 245 p. 124 illus., 38 illus. in color.) 311 $a3-030-49405-5 327 $aBrief History of Cavernous Malformations -- Definition and structure of cerebral cavernous malformations -- Molecular Biology of CCM -- Presentation -- Neuroimaging of Cerebral Cavernous Malformations -- Natural history of cavernous malformations -- Hemispherical Cavernomas in non-eloquent and eloquent areas -- Cavernoma-Related Epilepsy -- Surgery of deep-seated cavernous malformations -- Surgery of brainstem and cerebellar cavernous malformations -- Stereotactic Radiosurgery of Cavernous Malformations -- Cavernomas in children -- Cavernomas During Pregnancy -- Spinal cavernous malformations -- Intraorbital cavernous malformations. 330 $aThis book presents a complete up-to date description of cavernoma disease together with its known biology, genetics and variable clinical presentation. It facilitates improved decision-making on surgical intervention by presenting different cases, highlighting the particular features of lesions such as anatomical location, eloquences of adjacent brain and type of presentation that are important when making decisions. In addition, the reader is brought up to speed with developments in the neuroimaging and active treatment techniques, especially surgical resection and radiosurgery. Finally, the natural history of the disease is taken into account and compared to the possible benefits of surgical treatment. Cavernomas of the CNS: Basic Science to Clinical Practice provides a comprehensive overview from the fundamentals of this condition, to special patient groups such as children and pregnant women. Therefore, it is an indispensable resource for neurovascular surgeons, neurosurgical residents and neurologists. 606 $aNeurosurgery 606 $aVascular surgery 606 $aNeurology  606 $aNeurosurgery$3https://scigraph.springernature.com/ontologies/product-market-codes/H39000 606 $aVascular Surgery$3https://scigraph.springernature.com/ontologies/product-market-codes/H59133 606 $aNeurology$3https://scigraph.springernature.com/ontologies/product-market-codes/H36001 606 $aCirurgia vascular$2thub 606 $aMalformacions$2thub 606 $aCervell$2thub 608 $aLlibres electrňnics$2thub 615 0$aNeurosurgery. 615 0$aVascular surgery. 615 0$aNeurology . 615 14$aNeurosurgery. 615 24$aVascular Surgery. 615 24$aNeurology. 615 7$aCirurgia vascular 615 7$aMalformacions 615 7$aCervell 676 $a618.3268 702 $aBradá?$b Ond?ej$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aBene?$b Vladimír$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910416101103321 996 $aCavernomas of the CNS$92147575 997 $aUNINA