LEADER 03291nam 22005655 450 001 9910416096503321 005 20220316142057.0 010 $a3-030-56013-9 024 7 $a10.1007/978-3-030-56013-3 035 $a(CKB)4100000011406695 035 $a(MiAaPQ)EBC6321991 035 $a(DE-He213)978-3-030-56013-3 035 $a(PPN)250212315 035 $a(EXLCZ)994100000011406695 100 $a20200829d2020 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aBehavioral Pharmacology of the Cholinergic System$b[electronic resource] /$fedited by Mohammed Shoaib, Tanya L. Wallace 205 $a1st ed. 2020. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2020. 215 $a1 online resource (250 pages) 225 1 $aCurrent Topics in Behavioral Neurosciences,$x1866-3370 ;$v45 311 $a3-030-56012-0 327 $aA Review of the Cholinergic System and Therapeutic Approaches to Treat Brain Disorders -- Acetylcholine and Spontaneous Recognition Memory in Rodents and Primates -- Endogenous Acetylcholine and Its Modulation of Cortical Microcircuits to Enhance Cognition -- Cholinergic Signaling Dynamics and Cognitive Control of Attention -- Involvement of Nicotinic Receptors in Working Memory Function -- Nicotinic Receptors Underlying Nicotine Dependence: Evidence fromTransgenic Mouse Models -- Cholinergic Receptors and Addiction -- Behavioral and Molecular Basis of Cholinergic Modulation of Pain: Focus on Nicotinic Acetylcholine Receptors -- An Evolving Therapeutic Rationale for Targeting the ?7 Nicotinic Acetylcholine Receptor in Autism Spectrum Disorder -- Activators of ?7 nAChR as Potential Therapeutics for Cognitive Impairment. 330 $aThe molecular genetics of the cholinergic system including both muscarinic and nicotinic acetylcholine receptors, cholinesterases, acetylcholine synthesis and release have provided significant insights into potential targeting for pharmacological intervention. Cholinergic drugs are being used or evaluated for the treatment of diseases. Thus, this volume aims to broaden our understanding of the current state of cholinergic mechanisms to enable implementation of novel approaches for the development of more effective treatments. 410 0$aCurrent Topics in Behavioral Neurosciences,$x1866-3370 ;$v45 606 $aNeurosciences 606 $aNeurosciences$3https://scigraph.springernature.com/ontologies/product-market-codes/B18006 606 $aNeurociència cognitiva$2thub 606 $aSistema nerviós$2thub 606 $aFarmacologia$2thub 608 $aLlibres electrònics$2thub 615 0$aNeurosciences. 615 14$aNeurosciences. 615 7$aNeurociència cognitiva 615 7$aSistema nerviós 615 7$aFarmacologia 676 $a591.188 702 $aShoaib$b Mohammed$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aWallace$b Tanya L$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910416096503321 996 $aBehavioral Pharmacology of the Cholinergic System$92546176 997 $aUNINA