LEADER 05193nam 22007215 450 001 9910411946003321 005 20220516094354.0 010 $a3-030-46725-2 024 7 $a10.1007/978-3-030-46725-8 035 $a(CKB)4100000011325551 035 $a(DE-He213)978-3-030-46725-8 035 $a(MiAaPQ)EBC6270577 035 $a(PPN)26914742X 035 $a(EXLCZ)994100000011325551 100 $a20200701d2020 u| 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aCardiovascular Calcification and Bone Mineralization /$fedited by Elena Aikawa, Joshua D. Hutcheson 205 $a1st ed. 2020. 210 1$aCham :$cSpringer International Publishing :$cImprint: Humana,$d2020. 215 $a1 online resource (XXI, 563 p. 108 illus., 102 illus. in color.) 225 1 $aContemporary Cardiology,$x2196-8969 311 $a3-030-46724-4 327 $aPart I. Cardiovascular Calcification -- Chapter 1. Pathology of Arterial and Valvular Calcification -- Chapter 2. Developmental Pathways in Cardiovascular Calcification -- Chapter 3. Differential Mechanisms of Arterial and Valvular Calcification -- Chapter 4. Calcification in Aortic Valve Replacement -- Chapter 5. Role of Extracellular Vesicles in Cardiovascular Calcification -- Chapter 6. Biomechanics, Mechanobiology, and Cardiovascular Calcification -- Chapter 7. Cardiovascular Calcification in Diabetics -- Chapter 8. Cardiovascular Calcification in Chronic Kidney Disease -- Chapter 9. Cardiovascular Calcification in Peripheral Artery Disease -- Chapter 10. Cardiovascular Calcification in Pediatrics and Progeria -- Chapter 11. Imaging of Early Calcification -- Chapter 12. Calcification Paradox ? Bone vs Vascular Calcification -- Chapter 13. Clinical Trials in Cardiovascular Calcification -- Part II. Ectopic Calcification -- Chapter 14. Calcification in the Brain -- Chapter 15. Calcification in the Kidney -- Chapter 16. Calcification in the Liver and Lungs -- Chapter 17. Placental Calcification in Newborns and its Clinical Implications -- Chapter 18. Breast Cancer Microcalcification -- Chapter 19. Calcification Following Traumatic Blast Injury -- Part III. Bone Mineralization -- Chapter 20. Extracellular Matrix and Mineralization in Skeletal Development -- Chapter 21. Cellular Contributors to Bone Homeostasis -- Chapter 22. Biomechanics and Mechanobiology in Bone Remodeling -- Chapter 23. Osteogenesis Imperfecta and Congenital Disorders -- Chapter 24. Therapeutic Strategies for Pathological Bone Remodeling. 330 $aThe book covers the basic science and clinical aspects of cardiovascular calcification and bone mineralization. Cardiovascular calcification is the leading predictor of cardiovascular morbidity and mortality, with a predictive value more significant than blood lipid levels. The presence of calcific mineral in cardiovascular tissues alters biomechanical performance, increasing workload on the heart and potentiating atherosclerotic plaque rupture and subsequent heart attack and stroke. This book examines the role of calcification in cardiovascular disease covering topics such as calcification in the atherosclerotic plaques and aortic valves arteries and valves, aortic valve replacement, peripheral artery disease, imaging of early calcification and target discovery. In addition, various forms of ectopic calcification as well as mechanisms of bone mineralization are discussed. Cardiovascular Calcification and Bone Mineralization is an essential resource for clinicians, researchers, and other medical professionals in cardiology, pathology, and biomedical engineering. 410 0$aContemporary Cardiology,$x2196-8969 606 $aCardiology 606 $aPathology 606 $aBiomedical engineering 606 $aCardiology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33037 606 $aPathology$3https://scigraph.springernature.com/ontologies/product-market-codes/H4800X 606 $aBiomedical Engineering/Biotechnology$3https://scigraph.springernature.com/ontologies/product-market-codes/B24000 606 $aCalcificació$2thub 606 $aBiomineralització$2thub 606 $aMalalties del cor$2thub 606 $aMalalties dels ossos$2thub 606 $aCardiologia$2thub 608 $aLlibres electrònics$2thub 615 0$aCardiology. 615 0$aPathology. 615 0$aBiomedical engineering. 615 14$aCardiology. 615 24$aPathology. 615 24$aBiomedical Engineering/Biotechnology. 615 7$aCalcificació 615 7$aBiomineralització 615 7$aMalalties del cor 615 7$aMalalties dels ossos 615 7$aCardiologia 676 $a616.1 676 $a616.1 702 $aAikawa$b Elena$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aHutcheson$b Joshua D$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910411946003321 996 $aCardiovascular Calcification and Bone Mineralization$92226051 997 $aUNINA